Shock - General Flashcards

1
Q

Clinical definition of shock:

A
  1. SBP < 90
  2. MAP < 65
  3. With evidence of tissue hypoperfusion
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2
Q

Examples of tissue hypoperfusion:

A
  1. Mottled skin
  2. UO < 0.5 ml/kg/hr
  3. Lactate > 2
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3
Q

Signs of shock:

A
  1. Low GCS
  2. Agitation
  3. Pallor
  4. Cold peripheries
  5. Tachycardia
  6. Slow cap refill
  7. Tachypnoea
  8. Oliguria
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4
Q

General causes of shock:

A
  1. Inadequate CO - Hypovolaemia, pump failure
  2. Loss of SVR - Sepsis, anaphylaxis, neurogenic, endocrine failure
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5
Q

Cold & clammy suggests:

A
  1. Cardiogenic shock
  2. Fluid loss
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6
Q

Warm & well perfused with bounding pulse suggests:

A
  1. Septic shock
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7
Q

Mx septic shock:

A
  1. Take cultures before ABx - 2 ≈ peripheral blood culture plus, eg, urine, sputum, CSF
  2. Give ABx w/in 1st hour - Tazocin 4.5g tds + gentamicin 5mg/kg od + vancomycin 1g BD IVI if MRSA
  3. Fluid bolus of 20mL/kg crystalloid
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8
Q

Mx - Hypovolaemic shock:

A
  1. ID & Rx underlying cause
  2. Raise the legs.
  3. Give fluid bolus 10–15 mL/kg crystalloid
  4. No improvement after 2 boluses - consider ICU
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9
Q

Mx - Haemorrhagic shock:

A
  1. Stop bleeding
  2. Crossmatch blood - still shocked despite 2L crystalloids or class III/IV shock
  3. Give FFP alongside packed red cells
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10
Q

Mx - Heat exposure (heat exhaustion):

A
  1. Tepid sponging + fanning
  2. Avoid ice & immersion
  3. Resuscitate with high-sodium IVI - 0.9% saline
  4. ± hydrocortisone 100mg IV
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11
Q

What is SIRS?

A

Presence of 2 or more of the fol- lowing features:

  1. Temperature >38°C or <36°C
  2. Tachycardia >90bpm
  3. RR >20 breaths/min or PaCO2 <4.3kPa
  4. WBC >12≈109/L or <4≈109 /L
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12
Q

What is Sepsis?

A
  1. SIRS occurring in the presence of infection
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13
Q

What is severe sepsis?

A
  1. Sepsis with evidence of organ hypoperfusion - hypoxaemia, oliguria, lactic acidosis, or altered cerebral function
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14
Q

What is septic shock?

A
  1. Severe sepsis with hypotension (systolic BP <90mmHg or MAP ≤ 60)
  2. Despite adequate fluid resuscitation
  3. Or the requirement for vasopressors/inotropes to maintain blood pressure
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