Shelf - Random Flashcards
What stages do sleep terrors occur in?
3 and 4
What is the first line treatment for Tourette’s?
Clonidine
What is the treatment for enuresis?
Imipramine
What type of anemia is found in anorexia?
Normochromic
What is cyclothymia?
Cycling between depression and hypomania.
How man ECT treatments are effective for treating MDD?
6-12
Treatment for narcolepsy?
Modafinil, methyphenidate
REM changes in depression
Redistributes to first half of the night, latency decreases
What is the most serious complication in NMS?
Rhabdomyolysis
Side effect of Thioridazine that affects the eyes
Retinal pigmentation that can lead to blindness
What is the mechanism of Buspirone?
Partial 5HT antagonist
What is the most potent benzo?
Clonazepam
Dangerous side effect of carbamazepine?
Aplastic anemia, agranulocytosis
Dangerous side effect of lamotrigine
Stevens Johnson Syndrome
Dangerous side effect of valproic acid
Hepatic failure
Mirtazapine Mechanism
Alpha-2 antagonist which increases norepinepherine and serotonin
All AP known to: (2)
Lower seizure threshold, prolong QT
Aripiprazole mechanism
Partial DA agonist
Dangerous ziprasidone Side Effect
QT prolongation
SNRIs
Venlafaxine and duloxetine, increase 5HT and NE, good for comorbid pain syndrome
Which SSRI has the longest half-life?
Fluoxetine, low risk of discontinuation
Buspirone Mechanism
Partial 5HT agonist
Buproprion Mechanism
NE/DA reuptake inhibitor, avoid in seizure disordered patient and anorexia
Nefazadone/Trazadone Mechanism
Antagonism of 5HT2 and partial agonism of 5HT1
Therapeutic ranges of mood stabilizers
Li - .8-1, carbamazepine - 8-12, valproic acid - 80-120
Serious lamotrigine side effect
Steven Johnson Syndrome
Which drug is an autoinducer?
Carbamazepine
Benzo with the shortest half-life
Alprazolam
What other drugs cause an increase in lithium levels? A decrease?
Increase - NSAIDs, diuretics, Decrease - osmotic diuretics