sft GI Cytology

Question 1

On right image, what cell types are the two different arrows pointing to? Functions?

Answer 1

Straight arrow points to chief cells (releases pepsinogen and chymosin); curved arrow points to a parietal cell (secretes HCl and IF)

Question 2

In GI tract, dx? Buzz word?

Answer 2

Giardia; falling leaves

Question 3

In GI tract, DX?

Answer 3

Enterobius vermicularis on left; Strongyloides on right

Question 4

CMV vs HSV nuclear inclusions

Answer 4

CMV has Cowdry type A (dense inclusion surrounded by halo); HSV has Cowdry type B (multinucleation, ground glass, marginated chromatin)

Question 5

Esophagus, dx?

Answer 5

Barrett esophagus without dysplasia

Question 6

Esophagus, dx?

Answer 6

Esophageal adenocarcinoma

Question 7

Esophagus, dx?

Answer 7

SCC, 2nd pic is poorly differentiated

Question 8

Stomach cytology, dx?

Answer 8

Intestinal metaplasia

Question 9

Stomach cytology, dx?

Answer 9

H. pylori

Question 10

Stomach cytology, dx?

Answer 10

Gastric adenocarcinoma

Question 11

Stomach cytology, clue?

Answer 11

DLBCL, black arrows are lymphoglandular bodies

Question 12

Stomach cytology, dx?

Answer 12

MALToma (requires flow/IHC), caused by H. pylori and treated by its eradication; lymphocytes polymorphous but atyipical

Question 13

Bile duct brushing, diagnoses?

Answer 13

1st pic is reactive, 2nd is adenocarcinoma

Question 14

Diagnoses?

Answer 14

1st pic is neuroendocrine carcinoma, 2nd is high-grade lymphoma, which can be a mimic