SF - Introduction to pharmacology Flashcards

Definitions. Why drugs are administered. Why some drugs do not work.

1
Q

What is the definition of drug?

A

A chemical substance of known structure, other than a nutrient or an essential dietary ingredient, which, when administered to a living organism, produces a biological effect.

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2
Q

What is the definition of pharmacology?

A

The study of how drugs interact with biological organisms.

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3
Q

What is the definition of medicine?

A

A chemical preparation which usually contains one or more drugs and which is administered with the intention of producing a therapeutic effect.

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4
Q

What is the definition of pharmacokinetics?

A

A branch of pharmacology concerned with the movement of drugs within the body.

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5
Q

What is the definition of pharmacodynamics?

A

The effect of the drugs on the body.

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6
Q

Why might a drug not have the desired effect?

A
  • Insufficient selectivity.
  • Changes in structure and function.
  • Lack of knowledge of the disease process.
  • Species variability.
  • Drug interactions.
  • Idiosyncratic reactions.
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7
Q

What is the therapeutic index?

A

Quantitative measurement of the relative safety of a drug.

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8
Q

What happens when a drug is administered?

A
  • Absorption.
  • Distribution
  • Exertion of pharmacological effect.
  • Metabolism.
  • Excretion.
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9
Q

Where in the cell do drugs act?

A
Ion channels.
Membrane receptors.
Intracellular receptors.
Intracellular enzymes.
Transporter proteins.
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