LW - The immune system

Question 1

What is the definition of immunopathology?

Answer 1

Tissue damage caused by an excessive immune response.

Question 2

What is the definition of autoimmunity?

Answer 2

The inability to distinguish self from non-self.

Question 3

What is the definition of an allergy?

Answer 3

The inappropriate response to an environmental agent.

Question 4

What is the definition of immunotherapy?

Answer 4

Describes the treatment where the immune response is being stimulated.

Question 5

What is the main functions of a macrophage?

Answer 5

Kill intracellular pathogens.

Question 6

What is the main functions of a neutrophil?

Answer 6

Kills rapidly dividing bacteria.

Question 7

What is the main functions of an eosinophil?

Answer 7

Kills parasites.

Question 8

What is the main functions of a NK cell?

Answer 8

Kills virus-infected cells.

Question 9

What is the main functions of a mast cell?

Answer 9

Triggers an inflammatory response.

Question 10

What is the main functions of a dendritic cell?

Answer 10

Activates the adaptive immune response.

Question 11

What are the cellular components of the innate immune response?

Answer 11

Phagocytes.
Macrophages.
Neutrophils.
Eosinophils.
Basophils.
Mast cells.
NK cells

Question 12

What are the soluble factors of the innate immune response? What is the function of each of them?

Answer 12

Complement - coats pathogens with cells that the innate immune system can attack.
Acute phase - similar to complement proteins.
Interferons - activates cells to produce anti-viral proteins.

Question 13

What are the components of the adaptive immune response?

Answer 13

T-cells
B-cells
Immunoglobulins
Dendritic cells

Question 14

How do dendritic cells link the innate immune response and the adaptive immune response?

Answer 14

• Take up microbial agents at the site of infection.
• Become activates and travel to lymph nodes.
• Activates naive T-cells in the lymph nodes.