Sexually Transmitted Infections Flashcards

1
Q

What are some of the complications of HPV?

A

Cervical carcinoma
Urogenital Warts
Laryngeal papillomas

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2
Q

Describe the HPV vaccine

A

Based on VLP1 (major capsid protein)
2 killed vaccines available
Given to girls age 12-13
Protects against most cases of cervical cancer

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3
Q

What are the features of chlamydia trachomatis bacterium?

A

Obligate, intracellular organism

Gram negative

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4
Q

What are some of the consequences of chlamydia infection?

A

Trachoma - ocular infection in neonates
Genital infections
Lymphogranuloma venereum
Cancer

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5
Q

What is Reiter’s syndrome?

A

Complication of chlamydia causing arthritis, urethritis and conjunctivitis

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6
Q

How is a yeast infection treated?

A

Oral fluconazole

Topical nystatin

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7
Q

What is trichomonas vaginalis?

A

Anaerobic, single cell, flagellated protozoa that attaches to the squamous epithelium

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8
Q

What are the features of trichmoniasis?

A

Yellowish vaginal discharge

Infection of vagina and urethra

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9
Q

Describe the pathogen Neisseria gonorrhoeae

A

Gram negative, intracellular diplococcus
Human only host
Infects epithelial cells of mucous membranes of GU tract or rectum

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10
Q

What are the characteristics of gonorrhoea?

A

Discharge in males and females
Rectal infections in homosexuals
Oral pharyngitis from oral sex
Disseminated infection causing arthritis

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11
Q

What is ophthalmia neonatorum?

A

Conjunctivitis contracted by newborns during delivery
Mother infected with chlamydia or gonorrhoea
Can cause blindness without treatment

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12
Q

What are the symptoms of gonorrhoea in females?

A
Dysuria 
Rectal infection 
PID
Pharyngeal infection 
Post coital bleeding 
Septic arthritis
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13
Q

What are the symptoms of gonorrhoea in males?

A
Urethral discharge 
Anal discharge, pain and bleeding 
Epididymal tenderness
Pharyngeal infection 
Septic arthritis
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14
Q

What is the primary stage of syphilis?

A

Hard genital or oral ulcer at site of infection after about 3 weeks

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15
Q

What is the secondary stage of syphilis?

A

Red maculopapular rash anywhere, plus pale moist papules in urogenital region and mouth

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16
Q

What is the tertiary stage of syphilis?

A

Degeneration of the nervous system

Granulomas in liver, skin and bones

17
Q

What is congenital syphilis?

A

Placental transfer after 10-15 weeks of pregnancy
Infection can cause death or spontaneous abortion of foetus
Survivors develop secondary syphilis symptoms

18
Q

What pathogen causes chancroid?

A

Haemophilus ducreyi

19
Q

What is chancroid characterised by?

A

Painful genital ulcers

20
Q

What is used to treat gonorrhoea?

A

Ceftriaxone

21
Q

What is used to treat chlamydia?

A

Azithromycin and doxycycline

22
Q

What are the viral features of HIV?

A

Spherical
Enveloped
RNA genome
Retrovirus - uses reverse transcriptidase to make DNA from RNA