Parturition Flashcards

1
Q

What is the Estimated Date of Delivery?

A

40 weeks from the first day of Last Menstrual Period

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2
Q

When is pre-term and post-term?

A

Pre-term is before 37 weeks

Post-term is beyond 42 weeks

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3
Q

How can the first trimester ultrasound be used to date pregnancy?

A

Measurement of gestational sac volume and crown-rump length

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4
Q

What is the ultrasound in the second trimester for?

A

Anomalies and growth

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5
Q

How is the pregnancy state maintained i.e. labour prevented?

A

Gap junctions down regulated
Oxytocin receptors down regulated
Cervix composed of collagen and ground substance (fibrous)
Low level of prostaglandin biosynthesis

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6
Q

What causes initiation of labour?

A

Increased oestrogen towards the end of pregnancy causes uterine contractions
Increased prostaglandin production
Increase cytosol-free calcium (for contraction)
Oxytocin is released from pituitary

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7
Q

What is the Ferguson reflex?

A

The pressure of the foetus pushing down the the pelvic floor stimulates the posterior pituitary to release oxytocin

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8
Q

What occurs during cervical ripening?

A

Prostaglandin synthesis increases
Increased water content of glycoamioglycan matrix
Myometrial activity causes ‘effacement’ and thinning of cervix
Relaxin upregulates matrix matalloproteinases that breakdown collagen

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9
Q

What are Braxton hicks contractions?

A

Uncoordinated, non painful contractions

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10
Q

What does primiparous mean?

A

First birth

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11
Q

What happens in the first stage of labour?

A

Onset of regular contractions –> fully dilated cervix

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12
Q

What happens in the latent phase of stage 1 of labour?

A

Onset of painful contractions (5-10 minute intervals)
Cervical ripening and effacement
Cervix slowly dilates up to 3-4cm

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13
Q

What happens during the active phase of stage 1 of labour?

A

Cervix dilates 0.5-1cm per hour
Increase in frequency and strength of contractions
Presenting part descends
Rupture of membranes

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14
Q

What happens in the second stage of labour?

A
Cervix fully dilated (10cm)
Contractions stronger and every 2-5 minutes 
Presenting part descends
Women has an urge to bear down
Ferguson reflex occurs 
Delivery
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15
Q

What happens in the third stage of labour?

A

Expulsion of the placenta and membranes

Normally takes 5 minutes

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16
Q

What causes separation of placenta from endometrium?

A

Forceful uterine contraction cuts of placental bed which reduces bleeding

17
Q

Where are prostaglandins released from?

A

Uterine decidual cells

18
Q

What is the function of prostaglandins?

A

Stimulate uterine contractions
Soften, thin and dilate cervix
Potentiate contractions induced by oxytocin
Increase number of gap junctions

19
Q

What is the function of oxytocin?

A

Triggers phospholipase C cascade resulting in release of Ca2+ from SR stores in uterine smooth muscle –> causing contraction
Stimulates PGF2a production
Constricts uterine blood vessels at site of placenta
Foetal oxytocin induces labour

20
Q

Where is relaxin produced?

A

CL, placenta, decidua

21
Q

What is the role of relaxin in labour?

A
Increases right before labour 
Softens ligaments (via collagen metabolism) and helps cervix dilate
22
Q

How may mechanical stretch affect labour?

A

Stretch of uterus by foetus may stimulate uterine contractions via a smooth muscle stretch reflex

23
Q

Explain the positive feedback in uterine contractions

A

Uterine contractions stimulate prostaglandin release which increases intensity of uterine contractions
Uterine contractions stretch the cervix which stimulates oxytocin release and further uterine contractions

24
Q

What are the 4 stages of delivery?

A

Engagement and flexion of the head
Internal rotation
Delivery by extension of head - nose scrapes blanket
Delivery of shoulders

25
Q

What is breech?

A

Buttocks first

26
Q

What is external cephalic version?

A

Manipulation of foetus through abdomen from breech to cephalic presentation
Aims to reduce C-sections for breech

27
Q

What is a partograph?

A

Used to measure vital signs of mother and foetus during labour