Sexually transmitted infection (STI)

Question 1

What are some external Infections?

Answer 1

• Condylomata (genital wats, HPV)
• Herpes (2)
• Chancroid
• Granuloma

Question 2

Genital Warts (Condylomata)

Answer 2

• HPV
• Persistent
• can be asymptomatic
• types 16& 16: associated with genital cancers
• recent vaccine development

Question 3

Genetal Hepes

Answer 3

• HSV 2
• related to chickenpox & cold sores
• genital ulcers
• grows in neurons
• can remain dormant in neurons for years
• can reactivate and spread

1. Penetration of virus onto skin
2. Local replication & entry of virus ontp cutaneous neurons
3. centripetal migration in axil of uncoated nucleocuspid
4. synthesis of infectious virons
5. cetrifugal migration to epidermis

Question 4

Bacterial Diseases of external Genetialia

Answer 4

• Chancroid
  
  • Haemophilus ducreyi
• Granuloma inguinale (genital ulcers)
  
  • Calymmatobacterium

Question 5

Vaginal infections

Answer 5

• Candidiasis
• Trichomoniasis
• Bacterial vaginitis

Normal bacterial flora:

• lactic-acid producing bacteria
• helps growth of other bacteria

Question 6

What causes Candidiasis / Thrush?

Answer 6

• ↓normal bacterial flora
• antibiotics
• ↑ estrogen/progesterone
• ↓ immune system activity

Results in inflammation, thick odourless discharge

Question 7

What is Trichomoniasis?

Answer 7

• Inflammation
• Frothy, green, yellow discharge
• tutular infertility and PID

Question 8

What is Chlamydia?

Answer 8

Chlamydia trachomatis

• Intracellular paracites
• signs at infection: hypertrophy, drainage
• signs of urinary tract infection: urinary frequencye, dyuria, discharge, bleeding
• signs of upper genital tract infection: uterine bleeding, abdominal/pelvic discomfort

May cause conjuctivitis, infertility, ectopic pregnancy

Question 9

Gonorrhea

Answer 9

Neisseria gonorrhoeae

• asymptomatic
• pain and discharge
• conjuctivitis

Question 10

What is Syphilis?

Answer 10

Trepnema pallidum

• Primary syphilis:
  
  • chancre
• Secondary syphilis:
  
  • skin rash
  • mucosal lesions
• Tertiary syphilis:
  
  • gumma lesions develoop in organs
  • CNS & heart affected

Question 11

Hepatitis B Virus

Answer 11

• dsDNA
• IVDU
• low risk: healthcare, close personal contact incl. sharing razors
• Prevention: vaccine

Question 12

Human Immunodeficiency Virus (HIV)

Answer 12

• ssRNA
• AIDS