Sexually Transmitted Disease Flashcards

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1
Q

A sexual history should be obtained from any patient presenting with symptoms of…?

A
Vaginitis
Urethritis
Epididymo-orchitis
Pelvic inflammatory disease
Proctitis
Ulcer/lumps on genitlas
Possible syphillis
Possible HIV seroconversion
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2
Q

What infections are screening for in a standard sexual health screen?

A

Chlamydia
Gonnorrhoea
Syphillus
HIV

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3
Q

How is a NAAT sample for chlamydia testing obtained from a woman?

A

Self swab of vagina

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4
Q

How is a NAAT sample for chlamydia testing obtained from a man?

A

Urine sample

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5
Q

How is a NAAT sample for chlamydia testing obtained from a MSM?

A

Urine sample

Self swab of throat and rectum

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6
Q

In what populations is gonorrhoea more common?

A

MSM
Afro-carribbean
Urban areas with deprivation

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7
Q

What type of bacteria is n.gonnorrhoeae?

A

Gram negative diplococcus

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8
Q

How is gonorrhoea spread?

A

Through mucous membranes

Through secretions

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9
Q

What are the signs and symptoms of gonorrhoea in men?

A

Urethral discharge and dysuria 2-5 days after exposure in men

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10
Q

What are the signs and symptoms of gonorrhoea in women?

A

Change in discharge, abdominal/pelvic pain, dysuria and altered bleeding in women

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11
Q

How is gonorrhoea treated?

A

1mg ceftriazone IM

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12
Q

Why should the test for gonorrhoea be repeated, 2 weeks after treatment?

A

To ensure cure as gonorrhoea is highly resistant

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13
Q

Who should be treated for gonorrhoea?

A

Positive test result
Clinical suspicion of gonorrhoea
Recent or ongoing sexual contact with gonorrhoea

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14
Q

What are the possible complications of gonorrhoea?

A
Epidiymo-orchitis
Prostatitis
Pelvic inflammatory disease
Disseminated gonococcal infection
Resistance
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15
Q

What is the most common bacterial STi in the UK?

A

Chlamydia

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16
Q

What are the risk factors for chlamydia infection?

A

<25 years old
New sexual partner
>1 sexual partner in a month
Inconsistent condom use

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17
Q

Some people will self-clear a chlamydia infection. T/F?

A

True

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18
Q

Chlamydia is usually asymptomatic in females but symptomatic in males. T/F?

A

False - it is usually asymptomatic in both men and women

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19
Q

What are the possible symptoms of chlamydia in men?

A

Discharge, dysuria and meatal discomfort

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20
Q

What are the possible symptoms of chlamydia in women?

A

Intermenstrual or post-coital bleeding

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21
Q

Chalmydia can present with proctitis. What are the symptoms of this?

A
Rectal pain
PR discharge
Rectal bleeding
Tenesmus
Constipation
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22
Q

How is chlamydia treated?

A

Doxycycline 100mg BD for a week

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23
Q

What are the symptoms of pelvic inflammatory disease?

A

Pelvic pain
Fever
Dys[areunia

24
Q

What are the complications. of chlamydia?

A
Tubal infertility 
Pelvic inflammatory disease
Ectopic pregnancy
Fizz-high-curtis syndrome
Epididymo orchitis
25
Q

When ids mycoplasma genitalium infection treated?

A

When patient or their partner has symptoms

26
Q

How is mycoplasma genitalium infection diagnosed?

A

NAAT - urine sample for men, self vaginal swab for women

27
Q

What symptoms/conditions can result from mycoplasma genitalium?

A

urethritis

pelvic inflammatory disease

28
Q

What is the causative organism of syphillis?

A

Treponema pallidum

29
Q

How is latent syphillis defined?

A

patient is asymptomatic but tests positive for syphillis

30
Q

How soon after exposure does primary syphillis present?

A

9-90 days

31
Q

Describe the presentation of primary syphillis

A

Presents 9-90 days after exposure

Single, painless ulcer (chancre) which many patients do not realise they have

32
Q

Describe the presentation fo secondary syphillis?

A

3 months to 2 years after exposure
Generalised rash which affects palms and soles
Muco-cutaneous lesions, condylomata lata, lymphadenopathy and fever

33
Q

Describe the presentation of tertiary syphillis?

A
Neurosyphilis (variety of neurological symptoms including cognitive symptoms)
cardiovascular syphilis (aortic valve disease, aortic aneurysm and aortitis)
gummatous syphilis
34
Q

How is syphylis diagnosed?

A

Microscopy/viral PCR swab of chancre
Bloods for antibody (stay positive even after completed treatment)
Rapid plasma reagin

35
Q

What antibiotic is used to treat syphilis?

A

Benzathin penicillin

36
Q

What is the causative organism of anogenital warts?

A

HPV

37
Q

Which strains of HPV most commonly cause anogenital warts?

A

6 and 11

38
Q

When are anogenital warts most likely to spread?

A

When warts are present

39
Q

What problems do anogenital warts cause?

A

Itch and aesthetic problems

40
Q

Patients with anogenital warts need to notify their partner and previous partners. T/F?

A

False since there is such a high population prevalence of the virus but condoms should be used to prevent further transmission

41
Q

How are anogenital warts treated?

A
Cryotherapy
Topical treatments (podophyllotoxin or imiquimod)
Surgical excision (rarely required)
42
Q

What strains of the virus usually cause herpes simplex virus infection?

A

Types 1 and 2

43
Q

How is herpes simplex virus diagnosed?

A

Viral PCR swab

44
Q

What are the possible complications of herpes simplex virus?

A

CNS infection
Balanitis
Proctitis
Urinary retention

45
Q

What is the risk of herpes simplex virus infection in pregnancy?

A

If this is the first infection then there is a risk of neonatal infection

46
Q

How is herpes simplex virus treated?

A

Aciclovir

47
Q

What group of patient is particularly susceptible to trichomonad vaginalis infection?

A

Black women

48
Q

What are the symptoms of trichomonas vaginalis in women?

A
Vaginal discharge - frothy, yellow
Significant vulval itch
Dysuria
Offensive odour
Strawberry cervix
49
Q

What are the symptoms of trichomonas vaginalis in men?

A

Asymptomatic usually

Can cause urethritis

50
Q

How is trichomonas vaginalis treated?

A

Metronidazole

51
Q

Describe the pathogenesis of scabies?

A

Mite excrement triggers a hypersensitivity reaction. Burrows occur especially in the web spaces wrists, elbows and nipples

52
Q

How is scabies treated?

A

5% permethrin or
0.5% malathion
Should be washed off after 24 hours

53
Q

How is phthirus pubis transmitted?

A

Close bodily contact

Lives on course body hair

54
Q

How is phthirus pubis treated?

A

0.5% Malathion

1% permethrin

55
Q

What are the benefits of regular sexual health. checks for MSMs?

A

Allows discussion of preventative measures (e.g. partner. choice, condom. use)
Raise awareness of HIV symptoms and indications for post exposure prophylaxis against HIV
Discussion re use of alcohol/drugs in relation to sex
Can address other concerns and signpost to other. services e.g. recreational drug use, ‘coming out’, relationship issues

56
Q

What can be done to minimise the. development of drug. resistant strains of gonorrhoea?

A

Rapid accurate diagnosis via microscopy and NAAT
Avoidance of blind. therapy with inappropriate. drugs
Partner notification to limit onward spread of resistant infection
Good regional formulary policies using an antibiotic known to cover >95% infections
Epidemuology monitor or and policy. reaction to.resistance data