Sexually Transmitted Bacterial Diseases

Question 1

Gonorrhea

Answer 1

• Neisseria gonorrhea, aerobic G- diplococcus
• causes acute suppurative genital tract infection
• have pili that contain protease that digests IgA
• creates copious pus and submucosal abscesses
• may result in infertility if left untreated
• PID and Fitz-Hugh-Curtis Syndrome in women (OUCH)

Question 2

Chancroid

Answer 2

• Haemophilus ducreyi, G- bacillus
• leading cause of genital ulcers in less developed regions
• hypothesized to facilitate spread of HIV
• enters through skin breaks
• tx: erythromycin

Question 3

Granuloma Inguinale

Answer 3

• Calymmatobacterium granulomatis, G- bacillus
• tropical ulcerating disease
• macrophages contain many bacteria (Donovan bodies)
• may cause genital elephantitis
• Abx effective if treated early