Sexual Health Flashcards

1
Q

What is the epidemiology of STIs?

A

Infection with more than one STI is common - if have Chlamydia, may very well have gonorrhoea - so check for all

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2
Q

Why is it important to ask about whether STI patients have had Abx in the past few months?

A

(depending on the Abx) May have partly treated the STI and give a false result on swab culture for example - need to wait a couple of weeks then repeat again

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3
Q

Why is it important to ask men about their last voiding?

A

Bacteria like Chlamydia are urethral colonising - if recently voided, will give poor swab - need to be about 1.5hrs to allow good colony growth

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4
Q

What might you find in examination of inguinal lymph nodes?

A

Painful lymph nodes - herpes

Non painful lymoh nodes - syphilis (also single ulcers on penis - Shankar? or kissing lesions)

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5
Q

What are the baseline tests for an asymptomatic sexually active woman?

A

Self taken vulvo-vaginal swab:
Gonorrhoea/chalmydia nucleic acid amplification test (NAAT; type of PCR)

Bloods:
HIV + Syphilis

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6
Q

What are the baseline tests for an asymptomatic sexually active men?

A

First catch urine:
Important to be first catch as will be flushing of urethral bacteria
Chlamydia + Gonorrhoea NAAT

Bloods:
HIV + Syphilis

Additional tests in men who have sex with men (MSMs):
Pharyngeal + rectal swabs for Chlamydia/Gonorrhoea
Hep B (+/- C) bloods

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7
Q

What are the baseline tests for a symptomatic sexually active women?

A

Vulvo-vaginal swab for Gonorrhoea + Chlamydia NAAT

High vaginal swab (wet & dry slides) for 
Bacterial Vaginosis (BV); Trichomonas Vaginalis (TV); Candida

Cervical swab for slide + Gonorrhoea culture

Dipstick urinalysis (If has dysuria)

Blood:
HIV + Syphilis

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8
Q

What are the baseline tests for a symptomatic sexually active men?

A

Urethral swab for slide + Gonorrhoea culture ad sensitivity

First void urine for Gonorrhoea + Chlamydia NAAT

Dipstick urinalysis (If has dysuria)

Blood:
HIV + Syphilis

MSMs:
Test as for asymptomatic MSM
+ urethral and rectal slides
+ urethral, rectal, pharyngeal culture plates

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9
Q

What do different discharges indicate?

A

Gonorrhoea - thick gloopy, yellow
Chlamydia - thinner, white
Candidiasis - cottage cheese curds - not smelly
Trichomonas - green/yellow frothy - offensive
BV - thin, white/grey - fishy on whiff test (KOH drop added to discharge)

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10
Q

What are the characteristics of some genital lesions?

A

Molluscum - round, pale swellings with small dot/pore in the middle

Genital warts - HPV - fleshy, soft, possible cauliflower appearance bumps

Syphilis - single, painless ulcer (chancre)

Herpes - multiple, white raised bumps that burst to leave open red sores

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11
Q

What does Gonorhoea look like under the microscope

A

G-ve diplococci

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12
Q

Who is offered Hep B screening?

A

MSM

Commercial sex workers (CSW) +
IVDUs (including past) and their sexual partners

People from high risk areas and their sexual partners - Africa, Asia, Eastern Europe

Aim to vaccinate if non-immune

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13
Q

What are double and triple swabs?

A

Double swabs include a NAAT swab to test for both chlamydia and gonorrhoea and a high vaginal charcoal swab to test for fungal and bacterial infections such as candida albicans and bacterial vaginosis

Triple swabs include an endocervical chlamydia swab (usually in a pink wrapper), an endocervical sample using a charcoal swab to pick up gonorrhoea and a third sample, using a charcoal high vaginal swab to test for fungal and bacterial infections.

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14
Q

How does confidentiality work in GUM?

A

Can’t tell anyone outside clinic, GUM stuff kept within clinic, not told GP (unless other professional involvement required e.g. in HIV?)

Can’t tell sexual partners what is going on, done formally though contact tracing - left for partner to tell

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15
Q

How does contact tracing work?

A

Contact identification: Once someone is confirmed as infected with a virus, contacts are identified by asking about the person’s activities and the activities and roles of the people around them since onset of illness. Contacts can be anyone who has been in contact with an infected person: family members, work colleagues, friends, or health care providers.

Contact listing: All persons considered to have contact with the infected person should be listed as contacts. Efforts should be made to identify every listed contact and to inform them of their contact status, what it means, the actions that will follow, and the importance of receiving early care if they develop symptoms. Contacts should also be provided with information about prevention of the disease. In some cases, quarantine or isolation is required for high risk contacts, either at home, or in hospital.

Contact follow-up: Regular follow-up should be conducted with all contacts to monitor for symptoms and test for signs of infection.

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16
Q

How does Chlamydia present?

A

Usually between 1-3 weeks post infection, symptoms may be persistent or self resolve - if resolves doesn’t mean is cured, may still be an infection risk

Men: 
Dysuria
Red, itchy urethral meatus 
Thin white non smelling discharge 
Dysparunia 
Painful testicles - epididymoorchitis

Women:
Most are asymptomatic
If they do present - as above + bleeding with sex or between periods
May end up with pelvic inflammatory disease, risk of infertility and ectopic pregnancies if untreated - why contact tracing is especially important

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17
Q

How do you treat Chlamydia?

A

1st line:
Doxycycline - 100mg PO BD for 7days
- contraindicated in pregnancy

2nd line:
Azithromycin - 1g PO on day one then 500mg OD for 2days

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18
Q

What are some complications of Chlamydia infection?

A

Reactive arthritis - cant see/wee/climb tree - TREATMENT?

Can cause infertility in women if left undiagnosed and untreated

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19
Q

How does Gonorrhoea present?

A

Asymptomatic - in 1/10 men and 50% of women

Thick yellow discharge from penis or vagina

Dysuria

Intermenstrual bleeding

If congenital - eye signs e.g. conjunctivitis, eye discharge

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20
Q

How is Gonorrhoea treated?

A

Should do MC+S before prescribing to check for resistance

Some options are:
Ceftriaxone 1g IM as a single dose
Ciprofloxacin 500mg PO as a single dose

Pharyngeal gonorrhoea is harder to get rid of than genital/anal

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21
Q

How does Syphilis present?

A

Bacterial infection= Treponema pallidum

4 stages:
Primary- lesion an the site of sexual contact = syphilitic chancre (painless, firm skin ulceration 1-2cm), solitary raised painless lymph node
Secondary- palmar-plantar erythematous rash (also whole body), systemic features of illness (fever, malaise, headache, weight loss)
Latent - split into early and late, late not as contagious, neither are symptomatic but still seropositive, may relapse
Tertiary- 1-46yrs later depending on manifestation, 3x main types: gummatous = soft tumour-like balls of inflammation in bones, skin, liver etc; neruosyphilis = dementia mimic (memory loss, personality change..), apathy seizures; cardiovascular = aortitis and aortic aneurysms

Also a congenital form - dental defects; 1-3yrs after birth = splenomegaly, fever, rash, neurosyphilis

22
Q

How is Syphilis treated?

A

Benzypenicilin - IM

Contact tracing, sex abstinence and condoms

23
Q

What is vaginal candidiasis? How does it present and how is it manged?

A

Caused by Candida albicans

Presentation:
Itching + reddening around the vulva
‘Curdy’ white discharge with a pH <4.5; no odour
Dysparunia

Management:
Topical clotrimazole cream

24
Q

What is Bacterial vaginosis? How does it present and how is it managed?

A

Caused by: an imbalance in natural national flora - reduction of lactobacilli and increased in e.g. gardinerella vaginalis

Presentation:
Offensive, thin, white/grey, ‘fishy’ smelling discharge
Clue cells on microscopy
Associated with premature birth so still needs managing if discovered

Management: metronidazole PO; avoid shower gels, douching etc that would upset the flora

25
Q

What is Trichomonas vaginalis? How does it present and how is it manged?

A

Caused by: trichomonas - flagellated Protozoa

Presentation:
Offensive, yellow/green, frothy discharge - copious
Vulvovaginitis
Strawberry cervix

Management: metronidazole PO

26
Q

What are some conditions that might present with lack or loss of sexual desire?

A

All disorders = cause distress

Male hypoactive sexual desire disorder:

  • Loss of sexual desire is the principle problem
  • Not secondary to other sexual difficulties
  • Does not preclude sexual enjoyment or arousal but makes the initiation of sex less likely

Female sexual interest/arousal disorder:

  • Low interest in initiating sex, low arousal
  • Vaginal dryness or failure of lubrication

Orgasmic disorder:

  • Orgasm either does not occur or is markedly delayed - persistent and recurrent
  • Can occur in men and women, more common in women

Sexual aversion disorder:
- Persistent or recurrent extreme aversion to and avoidance of all or almost all genital sexual contact with sexual partner which causes distress or interpersonal difficulty

27
Q

What are some chronic medical conditions that cause sexual desire disorders?

A

Obesity
CVD
DM
Anaemia

28
Q

What are some hormonal disorders that cause sexual desire disorders?

A

Men:

(a) Androgen deficiency
(b) Hypogonadism – various aetiolgoies
(c) Hyperprolactinaemia

Women:

(a) Androgen deficiency
(b) Hypothyroidism
(c) Hyperprolactinaemia
(d) Post pregnancy
(e) Addison’s disease
(f) Menopause (Vaginal or pelvic pain, Vaginal atrophy/dryness, Change in self image, mood, memory, cognition, Change in desire)

29
Q

What are some iatrogenic causes of sexual desire disorders?

A

Prescribed meds:

(a) Both: Antidepressants, antipsychotics; Beta blockers
(b) Male: Finasteride etc
(c) Female: Oral contraceptive; Tamoxifen

Surgery:

(a) (bilateral) orchidectomy
(b) (“) oophorectomy
(c) Pelvic floor weakness or damage

Also self-inflicted:
(a) Vaginal dryness through local irritants and douching

30
Q

What are some psychological causes of sexual desire disorders?

A

Psych conditions – depression, anxiety, substance misuse

Psych experiences – environmental, life events, trauma/abuse

Body image disorder

Couples sex script problems

Erotic dissatisfaction 
(a)	Women have more ‘erotic plasticity’ than men – men’s sexual patterns laid down earlier than women and remain fixed, women may need a change  

Couple relationship problems

31
Q

How do you manage sexual desire disorders?

A

Both:

  • Sensate focus – identify the couples sexual likes/dislikes etc
  • New sexual routines, lubricant, vibrators

Males:
- Testosterone replacement

Females:

  • Eros device – clitoral pump for increased arousal and enhanced ability to achieve orgasm
  • HRT
  • ?testosterone in some post menopausal
32
Q

What is erectile disorder?

A

Marked difficulty in developing or maintaining an erection suitable for satisfactory intercourse

33
Q

What are some aetiologies of erectile disorder?

A

i) Chronic medical: CVD, DM, neurological
ii) Hormonal disorders
iii) Iatrogenic - Post prostate surgery, prescribed meds – antihypertensives/antidepressants (SSRI)
iv) Age related changes – normalising
v) Ineffective sexual stimuli
vi) Pain
vii) Veno-occlusive disorder – mechanism for trapping blood in the penis isn’t effective = difficulty sustaining erections
viii) Psychological - Psych conditions; Performance anxiety including problems related to unhelpful use of pornography, ‘spectatoring’ (hyper aware of your own actions during sex); Couples script problems; Relationship problems or issues from previous relationships; Educational, cultural or religions matters

34
Q

What are some pharmacological treatments for erectile disorder?

A

Oral:

(a) Sildenafil
(b) Tadalafil etc

Injectable (intracavernous):
(a) Alprostadil

Intraurethral:

(a) Alprostadil MUSE (medical urethral system for erection) pellet
(b) Alprostadil cream

Patient education:

(a) Need sexual stimulation to work
(b) Work best on an empty stomach
(c) Need to wait 45-60 mins
(d) Efficacy improves from the first-eighth dose

35
Q

What are some non-pharmacological treatments for erectile disorder?

A

Vacuum device

Penile/scrotal rings

New stimulating routines ie enhancing lubricants, vibrators

Kegel exercises

36
Q

What financial implications for the treatment of erectile disorder?

A

Can patients afford?

Some are exempt – DM, MS, PD, prostate Ca, pelvic/spinal cord injuries, dialysis, post prostate/pelvis/kidney surgery

Frustrations – can only be prescribed 4 doses/month for some tablets

37
Q

What is rapid ejaculation?

A

The inability to control ejaculation sufficiently for both partners to enjoy sexual interaction

38
Q

What are some causes of rapid ejaculation?

A
Biological: 
Genetic susceptibility 
Penile hypersensitivity 
Hyperthyroidism 
Prostatitis 
Comorbid sexual problems 
Sympathomimetic medications 
Psych: 
Anxiety states 
Early learned sexual experiences 
Lack of experience, infrequent sexual activities 
Relationship issues 
Partner issues ie pain
39
Q

How do you treat rapid ejaculation?

A

Topical anaesthetic

Dapoxetine - SSRI

Couple psychosexual therapy: Normalising/Managing partner expectations

Behavioural interventions:
Stop/start technique and sensate focus
Practice point of inevitability
Kegels; buttock relaxations during intercourse

40
Q

What is delayed ejaculation?

A

On almost all sexual occasions either generalised or situational without the individual desiring delay there is a marked delay/infrequency/absence of ejaculation

If doesn’t happen at all = inhibited ejaculation disorder ie never ejaculated

IMPORTANT TO EXCLUDE RETROGRADE EJACULATION

41
Q

What are some aetiologies of delayed ejaculation?

A

Similar to erectile disorder:

Physiological e.g. trauma, surgery, age etc.

Psychological e.g. depression, masturbation technique, relationship or vulnerability factors

42
Q

What is retrograde ejaculation?

A

Sensation of ejaculation without the obvious passing of semen – passes into bladder instead

If voiding urine shortly afterwards – any milky substance? - Urine sample = spermatozoa + fructose

Damage to nerves/muscles surrounding neck of the bladder – failure to constrict upon ejaculation – prostate surgery/DM/MS/alpha blockers

Only an issue if wanting to conceive – possible need for IVF

43
Q

How do you treat delayed ejaculation?

A

PSGP (personal sexual growth programme?)

Individual or couple therapy

Kegels

Vibration/superstimualtion

44
Q

What is vaginismus?

A

Spasm of the pelvic floor muscles that surround the vagina causing occlusion of the vaginal opening; penetration is either impossible or painful

45
Q

What are some causes of vaginismus?

A

Physiological
Sore vulva ie thrush
Vulvodynia – chronic pain syndrome (burning/irritation) of vulva – upon touching (including tampon insertion) or constant, often without identifiable cause (autoimmune disorders, infection, neuropathy) and poor treatment prospects (do the usual things though)

Pain conditions or anticipation of pain

FGM

Congenital abnormality

Misinformation/mistaken beliefs:
Vagina too small/no opening
First intercourse will be painful
Fears of pregnancy

Religious or cultural issues

Previous abuse/trauma/negative experiences

Fear/dislike of partner/ Relationship dissatisfaction

46
Q

What is dysparenuia?

A

Pain during intercourse

Both men and women

Often attributed to local pathology – if possible then categorise under that

Only use this term if there is no primary nonorganic sexual dysfunction ie vaginismus, vaginal dryness

47
Q

What are some different causes for different locations of genital/sex pain?

A

Pain on manipulation:
Infection, injury, irritation, lesions, hypersensitivity

Introitus (on entry) pain:
Episiotomy/circumcision, recurrent infection, herpes, allergies, interstitial cystitis, urethritis, vaginal atrophy, menopause, poor lubrication, insufficient arousal, substance, penis size

Mid-deep vaginal pain:
Endometriosis, shortened vagina, retroverted uterus, pelvic tumour, adhesions, IBS, constipation

Also psychological and relational aetiologies

48
Q

How do you investigate and manage dyspareunia?

A

Investigate and treat any underlying cause - detailed Hx, physical examination, bloods etc

Vaginsmus - vaginal trainers (sequential dilatation of opening)

Therapy/PSGP

49
Q

What is Peyronie’s disease and how is it managed?

A

Connective tissue disease – growth of fibrous plaques in tunica albuginea

Pain + pain on sex, abnormal curvature, ED, loss of girth and shortening

Increasingly common with age, affecting about 10% of people, Dupuytren’s association

Management:
Some spontaneously improve, majority get worse and some are sable

Some drugs such as vitamin E and collagen elastase drugs – though variable efficacies

Penile traction (again variable efficacy)

Surgery – last resort; loss of length to occur; penile prosthesis may be appropriate

50
Q

What is hypospadias and how is it manage?

A

Urethral opening not at the usual location on head of penis – lower in the midline to varying degrees – embryological failure; urine can spray when passing

Usually detected in newborns on the NIPE

Treatment:
Surgery – to restore normal appearance and function, usually around 3 months of age

51
Q

What is aspermia? How does it differ from azoospermia?

A

Lack of semen with ejaculation - not azoospermia = no sperm cells

Associated with infertility; caused by retrograde ejaculation, androgen deficiency, ejaculatory duct obstruction

52
Q

What is a paraphilia and some examples?

A

Sexual attraction to a non-sexual thing or situation:

Urophilia/Coprophilia - sexual gratification involving urine and faeces

Masochism/sadism/sadomachism - sexual gratification from receiving pain or humiliation/inflicting pain or humiliation/both

Exhibitionism - sexual gratification of exposing oneself in public

Only count as disorders if it brings someone distress; also some are illegal e.g. exhibitionism, zoophilia, paedophilia