Sexual Dysfunction Drugs Flashcards
1
Q
PDE 5 Inhibitors
A
Enhances erectile fxn by increasing cGMP in presence of sexual stimulation
Improved sensation and satisfaction after 12 weeks in women too
2
Q
Sildenafil
A
PDE 5 Inhibitors
3
Q
Vardenafil
A
PDE 5 Inhibitors
4
Q
Tadalafil
A
PDE 5 Inhibitors
5
Q
Flibanserin
A
Post-synaptic 5HT1A agonist & 5HT2A antagonist = lowers 5HT & raises DA & noradrenaline
Decreased sexual dysfxn in hypoactive sexual desire disorder
SE may outweigh benefits
6
Q
Flibanserin SE
A
Syncope & hypoTN (worse w/alcohol)
Dizziness, somnolence
7
Q
Buproprion
A
May have good effect on hypoactive sexual desire. Not clear if this is outside the antidepressant effect