Sexual Development Flashcards
Genetic sex
x and y chromosomes
phenotypic sex
genitals form between 8-12 weeks
final maturation and sex characteristics continue through _____
puberty
Gonads are the same until
6 weeks of gestation
2 duct systems
wolfian
mullerian
wolfian duct leads to
testes
mullarian duct leads to
ovaries
which chromosome has the sex determining region (SRY)
Y chromosome
SRY produces
testes determining factor (TDF)
differentiation of gonads happens at
8-12 weeks
leydic cells
produce testosterone
Sertoli cells
eventually produce sperm
testosterone acts on wolfian ducts to develop ____
Internal genitalia (epididymis, seminal
vesicles, vas deferens
Converted to DHT to make penis, scrotum,
and prostate
Sertoli cells secrete ____
Mullerian Inhibiting substance/hormone (MIS/MIH) which cause regression of mullerian duct
Anything not conforming to
average patterns are usually
referred to as
differences of sex
development (DSD)