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PA3305- Mod 10 > sexual (8) > Flashcards

sexual (8) Flashcards

1
Q

what is the first test to do in women who are not menstruating

A

Human chorionic gonadotropin

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2
Q

what does HCG stim

A

stims test prod

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3
Q

What is hCG secreted by

A

secreted by placenta trophoblasts (can be measured 3 days post conception)

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4
Q

How is hCG typically meausred

A

Immunoassays
radioimmunoassays
radioimmunoassays
mass spectrometry

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5
Q

Other than prog what does hCG increase in (3)

A

germ cell cancer of the testes
hepatomas
lymphomas

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6
Q

what stims LH release and what does it stim

A

secreted in response to GnRH from hypothalamus
is a releasing hormone from the pituitary

Stims estrogen from corpus luteum in females + stims test prod from leading cells in males

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7
Q

When does LH peak in menstural cycle

A

Peaks at middle

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8
Q

When does LH increase/decrese

A

I- Testes/overy failed, precocious pub

D- Pituitary failure, hypothalamus failure, stress, anorexia

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9
Q

What does FSH do in m + w

A

from pituitary

-stims sertoli cells in testes in men, follicles in every of women

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10
Q

what hormone is used to look for testes failure in men and menopause in women

A

FSH

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11
Q

What is FSH increased and decreased in

A

I- testes/overy failure, precocious puberty

D- Pituitary failure, hypothalamus failure

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12
Q

what is prolactin released from and what does it do

A

From ant pituitary

-causes lactation, suppression of menstrual cycle

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13
Q

MC tutor that produces prolactin

A

prolactinoms

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14
Q

What are the 3 androgens measured

A

DHEA (DHEA-S)
Androstenedione
Testosterone (bilogically available test is free, not bound)

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15
Q

What is test made by

A

Leydig Cells

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16
Q

what is the hormone marker for adrenal hyperfunction + what is it used to dx

A

17 hydroxyprogesterone

-used in dx of congenital adrenal hyperplasia/ovarian tutors/polycytic ovarian diseases

17
Q

Where is progesterone produced and what does it do

A

produced by the corpus luteum in overy

  • prepares endometrium for implantation
  • prepares mammary glands to secrete milk

-increases in latter part of the menstrual cycle

18
Q

difficulty w hormone measuremenst

A
  • very small amounts have huge effects
  • some hormones come out in pulses
  • what hormones do depend on the hormone and other chemical in the milieu
19
Q

causes of precocious puberty in boys + girls

A

boys- congenital adrenal hyperplasia

girls- to early maturation of hypothalamus and pituitary

20
Q

Tests for precocious puberty

A

androgens or estradiol

–Gonadotropin releasing hormone stim test (healthy is a 0 response)

21
Q

what to do if teenager but no puburty

A

GnRH stim test

22
Q

test results in an XY individual

A

these imdv have lots of test but a defect in the receptor

  • excesss test is converted to estrogen feminizing the imdv
  • these imdv will be sterile
23
Q

What to check from if a menstuating women stops menses

A

-check for weight changes, life stresses, general illness, appearance

lab- preg test, prolactin, androgens, FSH

24
Q

Polycystic ovaries (congenital adrenal hyperplasia) results

A

Starts at puberty. Hyperandrogenism but not levels of virilizing tumors

-increased LH, normal FSH

25
Q

impotence probs causes

A

90% of those have blood flow probs (atherosclerosis, nerve damage, post prostatectomy)

26
Q

what is infiltility chategorized as

A

no conception after 1 year of unprotected sex

27
Q

initial lab for infirtility

A

Spermatozoa count and motility (60% should show progressive motility)

  • CBC
  • urinalysis
  • STIs
28
Q

causes of female infertility

A

No ovulation
antisperm antibodies
tubal and pelvic diseases

29
Q

Tests for ovarian failure

A

low serum oestrogen
high serum LH, FSH
serum prolactin

30
Q

Male infertility causes

A

Testicular failure
hypothalamic puberty
sperm autoantibody

31
Q

andropause symptoms

A

depression, lethargy, inability to conc
insomnia
irritability
loss of mm strength

32
Q

heamatoology changes in preg

A

blood volume increases by 40#
blood water increases by 6-8l
erythrocyte mass increases by 20-30%

33
Q

coagulation changes in prg

A

fibrinogen sig increase
prothrombin tim, APTT increases
plasminogen increases

34
Q

respiratory changes in preg

A

ox increases by 20%

35
Q

how to screen for down syndrome, spina bifida

A

downs- low levels of serum AFP

Spina- High levels of serum AFP

PA3305- Mod 10 (9 decks)

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