GI Diseases (2) Flashcards
saliva testing (4)
- endomysial antibody IgA
- Antitransglutaminase antibodies
- antigliadin antibodies
- free hormones
Test is lack of gastric acidity (and what does it mean)
Smell breath- if brewery smell (likely colonization from lactobacilli/yeasts)
-probs will be probs digesting so use tests for long term malnutrition
Tests for excess gastric acidity (2)
Hellicobacter pylori inf- measure both breath + serology (antibody)
Serum gastrin for Zollinger ellison cancer
H. Pylori tests (5)
- Endoscopy + biopsy
- IgG antibodies
- IgA antibodies
- Stool antigen
- Urea breath test
Gastric cancers risk factors
long term excess H pylori
diet(smoked meats)
What will you see for lab tests in zollinger-elison syndrome
Increased serum gastrin
Pancreatitis clinical picture
- upper abdominal pain
- steady, severe epigastric pain 1-4 hrs after a meal
- 80% mild
Pancretitis tests (4)
- Serum Amaylase-> 3x upper limit (lasts 3-5 days
- Serum Lipase-> Lasts 8-10 days
- Serum calcium dec
- Plasma glu vaiable
acute pancreatitis causes (3)
gallstones, alcohol abuse (80% of cases)
Viruses
What is the test for pancreatic cancer
Cancer antigen 19.9
duodenal vs gastric ulcer
pain later after meal (pain decreases 2-3 hrs)
-gastric ulcers will be immediat epain
Possible factors in malabsorption/maldigestion leading to malnutrition
- decreased gastric acid
- decreased intrincic factor
- decreased bile salts
- decreased pancreatic enzymes
- insufficient surface are (celiac)
- Pancreatic insufficiency
celiac disease (what is it, what does it cause, age)
- gluten sensitive enteropathy
- antigen in alpha gladin
- -causes vilous atrophy
- -children + 3rd/4th decade (bimodal distribution)
What is celiac associated w
- diabetes type 1
- iintestinal adenocacima
- non hodgekins
Tests for celiac disease (5)
- serum antigliadin antibodies
- serum antitransglutiminase
- serum endomysial antibodies
- increased fecal fat (cant absorb fats)
- decreased pro and albumin
what is the mc disaccharide deficiency disease
m/c lactose intolerance
tests for disaccharide deficiency diseases
- feed pt dissaccaride + test serum for one of the sugars
- hyrogen breath tests
blind loop syndrome- what is it
structural problems after surgery/diverticuli
-disturbed motility leading to bac overgrowth
Tests for blind loop syndrome
fecal fat increased
serum B12 dec
breath tests (labled CO2 released from carbs that the bac in excess prefer)
What are the large intestine diseases
Diverticular disease
Chrons
Ulcerative colitis
cancers
diverticulitis tests
- fecal blood
- leukocytes in feces
irritable bowel syndrome symptoms
- abdominal pain
- altering diarrhea, then constipation
Chrons disease tests
(whole gut involved)
- albumin, chemistry profile, CBC
- Yersinia enterocyitica antibody
Ulcerative colitis dx tests
colonosscopy is diagnostic
Tests for malnutrition if acute/chronic
acute- serum pre albumin
chronic- serum albumin dec, 24hr urine creatine decreases
Malabsorbtion tests (5)
- fecal fat test
- fecal microscopy
- xylose absorbtion test (CHO malabsorption)
- Breath tests (gases from bac overgrowth)
- Disaccahride def tests (lactose)
Itestinal cancers tests (4)
screening test– occult blood in feces
- serum carcinoembryonic antigen
- serum alpha foetoprotein (check from spread to liver)
- serum GGt (check for spread to liver)
What is vasoactive intestinal polypeptide and what is it associated w
clinical fx is uncontrollable diarrhea
-abnormal electrolytes are a fx of thsi
colon cancer advanced testing(3)
screening test= fecal occult blood
- carcinoembyonic antigen
- cancer antigen 50
