GI Diseases (2)

Question 1

saliva testing (4)

Answer 1

• endomysial antibody IgA
• Antitransglutaminase antibodies
• antigliadin antibodies
• free hormones

Question 2

Test is lack of gastric acidity (and what does it mean)

Answer 2

Smell breath- if brewery smell (likely colonization from lactobacilli/yeasts)

-probs will be probs digesting so use tests for long term malnutrition

Question 3

Tests for excess gastric acidity (2)

Answer 3

Hellicobacter pylori inf- measure both breath + serology (antibody)

Serum gastrin for Zollinger ellison cancer

Question 4

H. Pylori tests (5)

Answer 4

• Endoscopy + biopsy
• IgG antibodies
• IgA antibodies
• Stool antigen
• Urea breath test

Question 5

Gastric cancers risk factors

Answer 5

long term excess H pylori

diet(smoked meats)

Question 6

What will you see for lab tests in zollinger-elison syndrome

Answer 6

Increased serum gastrin

Question 7

Pancreatitis clinical picture

Answer 7

• upper abdominal pain
• steady, severe epigastric pain 1-4 hrs after a meal
• 80% mild

Question 8

Pancretitis tests (4)

Answer 8

• Serum Amaylase-> 3x upper limit (lasts 3-5 days
• Serum Lipase-> Lasts 8-10 days
• Serum calcium dec
• Plasma glu vaiable

Question 9

acute pancreatitis causes (3)

Answer 9

gallstones, alcohol abuse (80% of cases)

Viruses

Question 10

What is the test for pancreatic cancer

Answer 10

Cancer antigen 19.9

Question 11

duodenal vs gastric ulcer

Answer 11

pain later after meal (pain decreases 2-3 hrs)

-gastric ulcers will be immediat epain

Question 12

Possible factors in malabsorption/maldigestion leading to malnutrition

Answer 12

• decreased gastric acid
• decreased intrincic factor
• decreased bile salts
• decreased pancreatic enzymes
• insufficient surface are (celiac)
• Pancreatic insufficiency

Question 13

celiac disease (what is it, what does it cause, age)

Answer 13

• gluten sensitive enteropathy
• antigen in alpha gladin
• -causes vilous atrophy
• -children + 3rd/4th decade (bimodal distribution)

Question 14

What is celiac associated w

Answer 14

• diabetes type 1
• iintestinal adenocacima
• non hodgekins

Question 15

Tests for celiac disease (5)

Answer 15

• serum antigliadin antibodies
• serum antitransglutiminase
• serum endomysial antibodies
• increased fecal fat (cant absorb fats)
• decreased pro and albumin

Question 16

what is the mc disaccharide deficiency disease

Answer 16

m/c lactose intolerance

Question 17

tests for disaccharide deficiency diseases

Answer 17

• feed pt dissaccaride + test serum for one of the sugars

- hyrogen breath tests

Question 18

blind loop syndrome- what is it

Answer 18

structural problems after surgery/diverticuli

-disturbed motility leading to bac overgrowth

Question 19

Tests for blind loop syndrome

Answer 19

fecal fat increased
serum B12 dec
breath tests (labled CO2 released from carbs that the bac in excess prefer)

Question 20

What are the large intestine diseases

Answer 20

Diverticular disease
Chrons
Ulcerative colitis
cancers

Question 21

diverticulitis tests

Answer 21

• fecal blood

- leukocytes in feces

Question 22

irritable bowel syndrome symptoms

Answer 22

• abdominal pain

- altering diarrhea, then constipation

Question 23

Chrons disease tests

Answer 23

(whole gut involved)

• albumin, chemistry profile, CBC
• Yersinia enterocyitica antibody

Question 24

Ulcerative colitis dx tests

Answer 24

colonosscopy is diagnostic

Question 25

Tests for malnutrition if acute/chronic

Answer 25

acute- serum pre albumin

chronic- serum albumin dec, 24hr urine creatine decreases

Question 26

Malabsorbtion tests (5)

Answer 26

• fecal fat test
• fecal microscopy
• xylose absorbtion test (CHO malabsorption)
• Breath tests (gases from bac overgrowth)
• Disaccahride def tests (lactose)

Question 27

Itestinal cancers tests (4)

Answer 27

screening test– occult blood in feces

• serum carcinoembryonic antigen
• serum alpha foetoprotein (check from spread to liver)
• serum GGt (check for spread to liver)

Question 28

What is vasoactive intestinal polypeptide and what is it associated w

Answer 28

clinical fx is uncontrollable diarrhea

-abnormal electrolytes are a fx of thsi

Question 29

colon cancer advanced testing(3)

Answer 29

screening test= fecal occult blood

• carcinoembyonic antigen
• cancer antigen 50