Sex Determination Flashcards
Wolffian duct leads to
seminiferous tubule
Mullerian ducts leads to
fallopian tubes
blocking androgens leads to
female genetalia
46 XY Gonadal Dysgenesis absent SRY
breast development, no ovaries or testes - appears female
Turner’s Syndrome
45X no gonad development , cardiac abnormalities, multiple phyiscal abnormalities
Klinefelter syndrome
47 XXY - all variably masculanized
Male pseudohermaphroditisim
has deficient androgen synthesis or deficient andorgen action
Female psuedohermphroditism
forms congentital adrenal hyperplasia secondary to excess maternal androgen
androgen insensitivity
issue with androgen receptor, appears externally female, blind ending vagina, identifies woman
21 hydroxylase deficiency blocks what?
coritsol and estrogen production
treatment for 21 hydroxylase deficiency?
corticoids and then will develop normally
21 hydroxylase is unique in that
it is the only condition where females remain fertile
