Sex Chromosome Translocations

Question 1

Pattern if inactivation favors _______ amount of functional imbalance

Answer 1

Least

Question 2

Short stature genes on X__

Answer 2

P

Question 3

Ovarian function genes on X__

Answer 3

Q

Question 4

Breakage and reunion in Xq21.1 and Xq23-Xq28 results in

Answer 4

Gonadal dysgenesis

Question 5

Breakage and reunion in Xq26.1-q27 and Xq13.3-q21.1 associated with

Answer 5

Premature ovarian failure

Question 6

Regions that escape X inactivation

Answer 6

1. PAR1 (Xp22.3)
2. PAR2 (Xq)
3. Several other genes