Mitosis and Meiosis Flashcards

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1
Q

Polar microtubules

A

Overlap in the midline and are responsible for pushing the poles of the spindle apparatus apart

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2
Q

Bilvalent

A

A pair of homologs held together by chiasmata

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3
Q

Chiasmata

A

Positions where chromosomes touch and crossing over occurs

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4
Q

Pseudoautosomal region

A

Matching sequence on the X and Y chromosome that allows for crossing over

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5
Q

Kinetochore microtubules

A

Responsible for pulling the sister chromatids of each chromosome apart

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6
Q

Sister chromatids

A

Two identical strands of a replicated chromosome joined by the centromere

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7
Q

2 forms of genetic reassortment

A

Crossing over

Independent assortment

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8
Q

Mendel’s law of Segregation

A

Gametes contain only one homologous chromosome and therefore one gene for each trait

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9
Q

Chromosomes

A

Rod shaped structures of condensed nucleic acid material

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10
Q

Nondisjunction

A

Failure of two chromosomes in a pair to disjoin during anaphase of cell division (both go into 1 daughter cells)

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11
Q

Karyotype

A

Organized picture of chromosomes

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12
Q

Centrioles

A

Located in the centrosome and produces the microtubules

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13
Q

4 genetic counsequences of meiosis

A

Reduction in chromosome number
Segregation
Independent assortment
Crossing over

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14
Q

Spindle apparatus

A

Network of filaments overall responsible for separating chromosomes during cell division

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15
Q

Stages of cell cycle

A

G1 > S > G2 > M

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16
Q

Centrosome

A

Organelle that is the primary microtubular organizing center that splits and forms the spindle apparatus

17
Q

Mendel’s law of Independent Assortment

A

Chromosomes are inherited independently from other chromosomes

18
Q

Homologous Chromosomes

A

A pair of chromosomes inherited from different parents and generally carry the same genes in the same order but do not have the same DNA sequence

19
Q

Centromere

A

Constriction on a chromosome at which the sister chromatids are held together

20
Q

Kinetochore

A

Protein structure on the centromere to which the spindle fibers attach

21
Q

Astral microtubules

A

Radiate in all directions and aid in the spindle orientation immediately before mitosis

22
Q

4 important steps of prophase

A
  1. Chromosome condensation begins
  2. Less/highly condensed regions form
  3. Each chromosome contains 2 strands of DNA connected by centromere
  4. Centromeres divides and migrate to opposite poles of the cell
23
Q

3 important steps in prometaphase

A
  1. Disruption of nuclear envelope into membrane vestibles
  2. Spindle mictotubules enter nuclear region
  3. Kinetochore mature and attach to the kinetochore microtubules
24
Q

4 important steps of metaphase

A
  1. Nuclear membrane disappears
  2. Chromosomes become maximally condensed
  3. Kinetochore microtubules align chromosomes at equitorial plate midway between the poles of the cell
  4. Polar microtubules begin to associate in preparation for anaphase
25
Q

4 important steps of anaphase

A
  1. Centromeres abruptly separate
  2. Each sister chromatid is pulled to opposite pole by shortening of kinetochore microtubules
  3. Polar microtubules elongate, pushing the spindle apparatus further to cell pole
  4. The arrival of the chromosomes at the spindle pole marks the end of anaphase
26
Q

4 important steps in telophase

A
  1. Spindle apparatus begins to decondense
  2. Polar microtubules elongate, further separating the two poles
  3. Nuclear envelop begins to form around aggregated chromosomes at each pole of the cell
  4. Chromosomes decondense and nucleoli reappear
27
Q

List of metacentric chromosomes

A
1
2
3
19
20
28
Q

List of submetacentric chromosomes

A
4
5
6
7
8
9
10
11
12
16
17
18
X
29
Q

List of acrocentric chromosomes

A
13
14
15
21
22
Y
30
Q

Uniparental disomy

A

Both chromosomes are inherited from one parent