SETEVENS-JOHNSON Flashcards

1
Q

CAUSA PRINCIPAL

A

REACCION A MEDICAMENTOS

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2
Q

ANTIGENO ASOCIADO

A

HLA B12

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3
Q

LESION DE MENOS DEL 10%

A

SJS

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4
Q

LESIONES DEL 10-30%

A

SJS-NET

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5
Q

LESIONES > 30%

A

NET

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6
Q

MANIFESTACIONES CLINICAS

A

ERUPCION MORBILIFORME, DOLOROSA, GENERALIZADA

AMPOLLAS CON DESPRENDIMIENTO EPIDERMICO

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7
Q

MEDICAMENTOS DE MAYOR RIESGO PARA SU APARICION

A
  • ALOPURINOL
  • SULFAS
  • ANTIEPILEPTICOS (FENITOINA, FENOBARBITAL Y LAMOTRIGINA)
  • ANTIRETROVIRALES ( NEVIRAPINA, ABACAVIR)
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8
Q

CUANDO SE INDICA EL TRATAMIENTO EN UCI O UNIDAD DE QUEMADOS

A

CUANDO LA AFECCION ES MAYOR AL 10%

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9
Q

CUANDO SE INDICA ABORDAJE EN HOSPITAL DE 2DO NIVEL

A

CUANDO LA AFECCION ES MENOR DEL 10%

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10
Q

MANEJO INICIAL

A
  • LIQUIDOS PARENTERALES CON HARTAMANN O RINGER LACTATO

- ENOXAPARINA SC POR ALTO RIESGO DE TVP

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11
Q

FARMACOS CONTRAINDICADOS

A

GLUCOCORTICOIDES

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12
Q

FARMACO DE PRIMERA LINEA

A

INMUNOGLOBULINA INTRAVENOSA HUMANA

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13
Q

INTERVALO DESDE LA EXPOSICION AL MEDICAMENTO Y LA APARICION DE LAS LESIONES

A

DESDE UNOS DIAS HASTA 4 SEMANAS

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14
Q

CLINICA EN EL PRODROMO

A
FIEBRE
ARDOR DE OJOS
ODINOFAGIA
TOS
ARTRALGIAS/ARTRITIS
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