MELANOMA Flashcards

1
Q

DE DONDE SE ORIGINA

A

MELANOCITOS

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2
Q

FOTOTIPOS QUE SUELEN AFECTARSE

A

FITZPATRICK 1 Y 2

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3
Q

GENES COMUNEMENTE MUTADOS

A

CDKN2A Y CDK4

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4
Q

TIPO HISTOLOGICO MAS COMUN

A

NODULAR

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5
Q

TIPO HISTOLOGICO QUE ES EL SEGUNDO MAS COMUN EN MEXICO Y AFECTA PALMAS, PLANTAS Y SUBUNGUEAL

A

ACRAL LENTIGINOSO

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6
Q

SITIO MAS COMUN DE AFECTACION DE MELANOMA NODULAR

A

ESPALDA Y PIERNAS

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7
Q

ABCDE

A
A- ASIMETRIA EN 2 EJES
B- BORDES IRREGULARES
C- > 2 COLORES
D- DIAMETRO > 6 MM 
E- ELEVACION DE LA LESION
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8
Q

SIGNO CARACTERISTICO DE MELANOMA

A

SIGNO DEL PATO FEO

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9
Q

COMO SE HACE EL DIAGNOSTICO

A

BIOPSIA ESCISIONAL

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10
Q

CUANDO SE INDICA BIOPSIA INCISIONAL

A

CUANDO SON LESIONES GRANDES O SE LOCALIZAN EN CARA/ACRAL

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11
Q

MARCADOR QUE SE ENCUENTRA CLASICAMENTE EN ESTA PATOLOGIA

A

S-100

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12
Q

ESCALA UTILIZADA QUE SE BASA EN LA PROFUNDIDAD DE LA LESION EN MM

A

BRESLOW

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13
Q

ESCALA UTILIZADA QUE SE BASA EN LA INVASION ANATOMICA

A

CLARK

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14
Q

TRATAMIENTO DE MELANOMA EN ESTADIO IV

A

QT CON DACARBAZINA

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15
Q

TRATAMIENTO DE MELANOMA EN ESTADIO III

A

ESCISION + LINFADENECTOMIA Y SE PUEDE AGREGAR INTERFERON ALFA

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16
Q

TRATAMIENTO DE MELANOMA EN ESTADIO 0, IA, IB Y II

A

ESCISION

17
Q

CUAL ES FACTOR PRONSTICO MAS IMPORTANTE

A

LA INVASION DE GANGLIOS LINFATICOS

18
Q

SITIOS DE METASTASIS MAS COMUN

A

PULMON, HIGADO Y CEREBRO