Session 5- Absorption and Digestion Flashcards

1
Q

what is glucose absorbed with

A

sodium

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2
Q

what does isomaltase do

A

breaks 1,6 bonds in starch

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3
Q

what are the products of the breakdown of starch

A

glucose
matose
alphadextrins

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4
Q

what does lactose get broken down into

A

galactose and glucose

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5
Q

what does sucrose get broken down into

A

glucose and fructose

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6
Q

What transporter do galactose and glucose travel through in the apical membrane into the cell

A

SGLT1 with sodium

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7
Q

What transporter do galactose and glucose travel through in the apical membrane into the cell

A

SGLT1 with sodium

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8
Q

What transporter does fructose travel through to get in the cell

A

GLUT5

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9
Q

What transporter do glucose, fructose and galactose travel through on the basal membrane to get into the blood

A

GLUT 2

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10
Q

how are proteins broken down in the stomach

A

chief cells produce pepsinogen in the gastric glands which is converted to pepsin in the stomach lumen

pepsin converts the proteins into oligopeptides and amino acids

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11
Q

what do endopeptidases do

A

break down proteins in the centre

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12
Q

what do exopeptidases do

A

break down peptides at the end to make amino acids and short peptides

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13
Q

symptoms of B12 deficiency

A

neurological problems

megaloblastic anaemia

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14
Q

causes of b12 deficiency

A
lack of intrinsic factor 
hyperchlorhydria 
-inadequate stomach acid
not enough b12 in food
inflammation of terminal ileum- b12 absorbed here
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15
Q

symptoms of IBS

A
abdominal pain
bloating 
flatulence
constipation
diarrhoea
rectal urgency
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16
Q

what is coeliac disease

A

immunological response to gluten

  • wheat
  • rye
  • barley
17
Q

how does coeliac disease affect the gut

A
  • damages mucosa
  • flattening of villi
  • hypertrophy of crypts
  • lymphocytes in epithelium / lamina propria
18
Q

causes of coelic disease

A

genetic factor

19
Q

symptoms of coeliac disease

A
diarrhoea
weight loss
flatulence
anaemia
neurlogical symptoms
20
Q

how do we investigate coeliac disease

A

blood test-> IgA to smooth muscle endomysium and tissue

upper GI endoscopy -> duodenal biopsy -> mucosal pathology (reduced or absent villi)