Session 12 - Lecture 1 - Review Flashcards
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3 - General Advice
- Look at events in a chronological manner
- Take a step back;
- Think about ‘bigger picture’ of what the body is trying to achieve
- Anatomy & histology
- Think how structure relates to function
- See the links across units
- We are looking for demonstration of understanding concepts
- Hang the details onto that
- What is ‘normal’? What can go wrong?
{General advice - isn’t necessarily specific to repro
- firstly, particularly in repro – pattern – start, process and end to most things in repro – look at things that happen e.g. menstrual cycle, fertilisation, implantation, foetal development
2a. what is it that we want to happen and therefore how are we going to make that happen. 3. something to go over yourself – have a look at and be happy with – not much tips or tricks other than how structure of something relates to its function – no diff to the repro system – male and female anatomy e.g. pelvic floor – what is its function – how does structure relate to function. - Integrate
- If you can describe something to us as concept – understand concept, but you can hang detail – detail makes a lot more sense when you have overall concept of what’s happening.
5b. What is normal process / anatomy / sequence of events – what can interrupt that / go wrong in that process
Conceptual lecture – explain concepts and apply to diff types of pathologies and where things can go wrong}
5 - What are the SIMILARITIES in the development of the reproductive tract between male and female systems?
• Germ cells
- Migrate
- Drive development of the gonad
• Gonads
- Both descend
• Duct system
- Forms internal genitalia
{male and female, how we form those systems – might look slightly diff on outside, processes of that happening r similar and mirror each other.
1a. start in yolk sac and migrate
b. principle role - either make testis or ovaries.
2. both have gubernaculum which pulls them down into pelvis – just point at which they stop differ.
3. concept same for both – names and process might b diff.}
6 - What are the DIFFERENCES in the development of the reproductive tract between male and female systems?
• Gonad - Medulla vs cortex - Testes vs ovaries - Androgens & MIH vs neither • Duct system - Open vs closed - Mesonephric vs paramesonephric duct
{Diffs are perhaps obvious –
1a which bit develosp first – medulla (inside) or cortex (outside).
1c. 1b therefore do you get androgens & MIH (come as a pair together) - men both, women neither bc women don’t have testes so can’t secrete them
2a. female is open, fallopian not in contact with ovary – don’t fuse in same way, meaning open – to peritoneal cavity whereas closed in men.
2b. – mesonephric or Wolffian in men – or paramesonephric duct or Mullerian duct that develop in women – that then make sense to how internal genitalia looks.}
7 - Development of reproductive tracts - think about chronology -
What is the initial step for male and female reproductive development?
• Initial step is the same in males and females:
o Primordial germs cells migrate along retroperitoneum to the gonad at the urogenital ridge
{germ cells - live in yolk sac - make way up to back of abdo to urogenital ridge: migrates there to try and make gonad – gonad will determine everything else that happens along the way.}
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