session 10-Innate immunity Flashcards
what do INTERferons do?
INTERfere and inhibit viral replication
what do lysosomes do?
break down peptidoglycan in bacterial cell walls
what is opsonisation?
identify and locate invading particle to be phagocytosed by coating with antibodies or complement to render it foreign
what opsonises bacteria and promotes their phagocytosis?
fibronectin
what causes destruction of microorganisms directly or with the help of phagocytic cells?
complement
what suppresses viral replication and activated phagocytes?
alpha TNF
what do NK (natural killer) cells do and what type of immune system are they part of?
- recognise and kill abnormal cells by pumping proteases through pores
- non specific
- innate system
what is the role of macrophages and monocytes?
phagocytosis
antigen presentation to lymphocytes
what do neutrophils do?
phagocytic and anti bacterial
what do eosinophils do?
anti parasite and allergic response
what do basophils and mast cells do?
allergic response
what do transFERRIN and lactoFERRIN do?
deprive microorganisms of iron
give 4 features of innate immunity
- non specific
- no memory
- not enhanced by second exposure
- present from birth
which immune system lasts longer and which responds quicker but lasts for a shorter time?
innate-responds quickly lasts short time
adaptive-takes longer but lasts longer
