Session 1 - Exam 2 Flashcards

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1
Q

What is CHON?

A

CHON refers to the number of bonds the necessary elements of life can make. Carbon can make 4, hydrogen can make 1, oxygen can make 2, and nitrogen can make 3.

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2
Q

What is a carbohydrate?

A

A carbohydrate is carbons with attached water molecules (H20). Sugar molecules. They are the main form of energy and energy storage for living things.

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3
Q

How can you identify a carbohydrate?

A

A carbohydrate will be displayed as Cx(H20)y. For example, C6(H20)6 is glucose. The full formula for glucose is C6H12O6. In other words, a carbohydrate will have twice the number of hydrogens than oxygens. E.g. H 12 and O 6 from glucose.

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4
Q

What does saccharides mean? What are the main 3 monosaccharides?

A

Saccharides means sugars. Glucose, Fructose, and galactose. They are known as isomers because they have the same molecular formula but different arrangements.

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5
Q

How can you identify glucose (with reference to Alpha and Beta Glucose)?

A

Glucose has OH on the bottom of Carbon 4 (opposite to galactose). Alpha Glucose has OH on the bottom of Carbon 1, and Beta Glucose has OH on the top of Carbon 1.

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6
Q

How can you identify Galactose (with reference to Alpha and Beta Galactose)?

A

Galactose has OH on the top of Carbon 4 (opposite to glucose). Alpha Galactose has OH on the bottom of Carbon 1, and Beta Galactose has OH on the top of Carbon 1.

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7
Q

What is condensation?

A

2 molecules join to form a larger molecule, with the release of a water molecule (a water molecule is displaced).

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8
Q

What is hydrolysis?

A

Hydrolysis is the opposite of condensation (broken into 2 with the addition of a water molecule).

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9
Q

How can you identify a fructose (with reference to Alpha and Beta frucose)?

A

A fructose has a pentagon shape as opposed to the hexagonal shape of galactose or glucose. Alpha fructose has OH on the bottom and Beta fructose has OH on the top of the first carbon on the right.

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10
Q

What is a glycosidic bond? Describe the bonds for chains:

A

A glycosidic bond is a bond that joins a saccharide molecule and the hydroxyl group of an organic compound (hydroxyl group bonded to a hydroxyl group). 1- 4 bonds for chains are horizontal, 1 - 6 bonds are vertical.

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11
Q

What is sucrose?

A

Alpha glucose and beta fructose (it is a disaccharide)

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12
Q

What is a lipid?

A

A lipid is a hydroxyl group and a carboxyl group attached together. Fats and oils.

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13
Q

What is a functional group and what are the three main functional groups?

A

A functional group describes the function of an organic compound. The first group is the hydroxyl group (OH) (alcohol), the carboxyl group (COOH) (acids), and the amine group (NH2).

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14
Q

Describe the arrangement of COOH.

A

COOH is a carbon double bonded with an oxygen, and single bonded with OH. This in total is three bonds and therefore the final bond attaches it to the rest of the molecule (R).

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15
Q

Describe the structure of a lipid.

A

A lipid is a hydroxyl group bonded with three carboxyl groups through condensation.

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16
Q

What is saturated fat (a saturated carbon)?

A

A carbon that is attached to 4 different groups (because carbons have the ability to make 4 bonds).

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17
Q

What is unsaturated fat (an unsaturated carbon)?

A

A carbon that is attached to 3 or less groups (e.g. with a double bond or triple bond).

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18
Q

What are fatty acids and how can they be classified?

A

Fatty acids are a hydroxyl group bonded with a carboxyl group. They can be classified as saturated (each carbon with four groups), monounsaturated (one double bond), or polyunsaturated (multiple double bonds).

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19
Q

Why can a lipid’s structure be spreading/its tails are not straight lines? What does this mean?

A

The lipid has double bonds, which are shorter than regular bonds resulting in the bend of chains. Tails spreads apart so the molecules can’t be packed close together (it’s a liquid). Solids are things that can be packed close together, liquids are further apart.

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20
Q

If a lipid is a solid or liquid can tell you what?

A

When a lipid is solid it is a fat which means it is generally from an animal. When a lipid is liquid it is an oil which means it is generally from a plant. Furthermore, saturated lipids are generally fats (animals) and unsaturated lipids are generally oils (plants).

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21
Q

What is cis and trans fat (fatty acids)? Is it saturated or unsaturated?

A

They are both unsaturated. Cis and trans fat refers to the position of a hydrogen and carbon chains in relation to double bonding. In cis fat, the hydrogen and carbon chains are on the same side (they mirror each other). In trans fat, the hydrogen and carbon chains are on opposite sides (e.g. if the hydrogen is on the top of the first carbon then the hydrogen is on the bottom of the second carbon).

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22
Q

What is a phospholipid?

A

A phospholipid is where one acid group of a lipid is replaced by a phosphorus.

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23
Q

How many calories per gram are there for carbohydrates, lipids, and proteins?

A

Carbohydrates have 4 cal/g, lipids have 9 cal/g, and proteins have 4 cal/g.

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24
Q

What are omega 3 and omega 6?

A

Omega refers to the end of a chain of a lipid. Omega 3 is when there is a double bond between the 3rd and 4th carbons of a lipid. Omega 6 is when there is a bond between the 6th and 7th carbons of a lipid.

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25
Q

Just like lipids are fats in animals and oils in plants (generally), carbohydrates are what two things?

A

Carbohydrates store energy in starch for plants and glycogen for animals (generally).

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26
Q

Describe the building blocks of proteins.

A

Proteins are made up of amino acids. Lots of amino acids form polypeptides. Polypeptides are the main component of proteins (can consist of one or several polypeptide chains linked together –> can also include other molecules in their structure).

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27
Q

What is the primary structure of proteins?

A

There is an infinite amount of types of amino acids, but only 20 are found in living things. The arrangement of these 20 in their sequence (they can be in any order & there can be duplication) form a chain which is the primary structure of proteins.

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28
Q

What is the secondary structure of proteins?

A

The secondary structure is when you have a long peptide chain of amino acids, it starts to fold into either spiral (alpha) or pleated sheet (beta) formation.

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29
Q

What is a protein? What is the importance of structure?

A

A protein is the basis of body structures. They play critical roles in the body and are necessary for proper bodily function. Protein structure depends on amino acid sequencing and this structure is important because it plays a key role in the function of a protein (surface structure determines the protein’s function)

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30
Q

Why are proteins called polypeptides?

A

The bond between two or more bonded amino acids is called a peptide bond. Many peptides = polypeptides. Polypeptides are when many amino acids join up (proteins are made of many amino acids). They can be from a handful of amino acids to tens of thousands in length.

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31
Q

What does it mean for amino acids and fatty acids to be essential?

A

When something is essential is means that it cannot be made within the body, it has to be consumed. 9 of the 20 amino acids are essential.

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32
Q

What is an amino acid?

A

An amino acid is a central carbon with amine (NH2) on one side and acid (COOH) on the other (called a monomer/building block). Amino acids combine via condensation to form chains of amino acids and therefore form a protein. Amino acids can form very long chains because they have functional groups on both sides.

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33
Q

What is tertiary structure of a protein?

A

3D folding of the peptide chain (secondary structure) due to interactions between side chains or R groups.

34
Q

What is an R Group? What are the types of R Groups.

A

R group is an abbreviation of any molecule where a carbon or hydrogen atom is attached to the rest of the molecule, but it can be more complex than this. R groups allow more complex 3D structures (tertiary structure). The four types of R Groups are non-polar covalent, polar covalent, ionic groups, and sulfur groups.

35
Q

What is the quaternary structure of proteins.

A

Different tertiary chains coming together –> proteins made of several polypeptides, also known as sub-units.

36
Q

What is protein denaturation?

A

When chemical bonds holding a protein together are broken, and it can no longer hold a 3D shape/cannot maintain its molecular structure (only applicable for tertiary and quaternary structures). This can be caused by changes in temperature and pH outside the protein’s optimum range. Denaturation will usually lead to the loss of the protein’s function because shape determines function.

37
Q

Explain the protein functions: Enzyme

A

Catalyse (cause or accelerate a reaction by adding a catalyst) specific chemical reactions

38
Q

Explain the protein functions: movement

A

actin and myosin proteins in muscle fibres contract and relax

39
Q

Explain the protein functions: blood clotting

A

Protein makes blood turn gel-like/solidified which prevents excessive bleeding

40
Q

Explain the protein functions: transport

A

haemoglobin carries oxygen through the blood –> protein in red blood cells

41
Q

Explain the protein functions: membrane transport

A

Protein channels in the cell membrane which allow/stop things to pass through the membrane

42
Q

Explain the protein functions: hormones

A

chemicals messengers transported by blood (e.g. insulin)

43
Q

Explain the protein functions: immunity

A

lysosomes, anti-bodies attach to something that doesn’t belong, labelling it for removal

44
Q

What are fibrous proteins?

A

insoluble structural components that are elongated with a dominant secondary structure (they are a long strand)

45
Q

What are globular proteins?

A

soluble functional tools that have a spherical shape and a dominant tertiary structure (spherical/globe shaped). All chemical reactions take place within an aqueous environment, so most proteins that are not part of structure will be globular.

46
Q

For globular and fibrous proteins, what does it mean to be soluble or insoluble.

A

If something is soluble it can be dissolved/surrounded by water. Anything that needs to be transported has to be soluble because it needs to be carried by blood. Insoluble things are long and cannot be surrounded by water, things that are stored are insoluble.

47
Q

Describe the type, role, and function of Keratin.

A

It is fibrous, its role is structure, and it is a protective covering for hair, nails, etc.

48
Q

Describe the type, role, and function of Collagen. Describe it.

A

It is fibrous, its role is structure, and it is connective tissue of skin and tendons. Collagen is a rope like protein that gives strength to skin, blood vessel walls, ligaments, tendons, teeth, and bones.

49
Q

Describe the type, role, and function of Polymerase.

A

It is globular, its role is enzyme, and it catalyses DNA synthesis.

50
Q

Describe the type, role, and function of Insulin.

A

It is globular, its role is communication, and it is a hormone of glucose homeostasis (it regulates glucose uptake into the cells).

51
Q

Describe the type, role, and function of Haemoglobin

A

It is globular, its role is transport, and it transports oxygen.

52
Q

Describe the type, role, and function of Anti-bodies.

A

It is globular, its role is the immune system, and it is protection from pathogens.

53
Q

Describe the protein Immunoglobulin.

A

Also known as anti-bodies, they bind bacteria to other pathogens, marking them for immune cells to destroy.

54
Q

Describe the protein Rhodopsin.

A

pigment protein in the rod cells of the eye, responsible for vision in low light levels

55
Q

Describe the protein spider silk.

A

strong fibrous protein that is extensible and resistant to breaking

56
Q

Describe the proteins actin and myosin.

A

generate movement in muscle tissue by sliding across each other to shorten or lengthen the entire muscle

57
Q

What are enzymes?

A

Biological catalysts that speed up the rate of chemical reactions within the cell. Most are globular proteins. They are interesting because they do not change or are not consumed by the reaction and can be reused. Every reaction needs a specific enzyme to occur.

58
Q

What is an active site of an enzyme?

A

Region on the surface of the enzyme which binds to a substrate molecule. It is a specific shape which is a match for the substrate that generally will allow the reaction to work faster. Some enzymes might change the shape of molecules (substrate) to make reactions faster/more likely to occur.

59
Q

What is a substrate?

A

Molecule acted upon by an enzyme (molecule that an enzyme reacts with). The reaction generally splits the substrate into the products, e.g. separation of glucose and galactose.

60
Q

Why is orientation important for substrates and active sites (enzymes).

A

The substrate and the active site have to collide in the correct orientation for the reaction to occur.

61
Q

Describe the 3 classes of enzymes and why we classify them.

A

Enzymes are broadly classified into groups based on the type of reaction they help catalyse. Hydrolases catalyse hydrolysis reactions by adding water. Isomerases catalyse structural shifts in a molecule, causing a change in shape. Ligases catalyse the synthesis of 2 molecular substrates into one molecule (condensation reactions).

62
Q

Why can enzyme reactions be complex?

A

Enzymes can catalyse a single reaction or be part of a more complex (multi-step) metabolic pathway involving multiple enzymes (at different steps in the process)

63
Q

What happens to monosaccharides, fatty acids, and amino acids when condensation occurs (they are bonded to themselves).

A

Monosaccharides turn into polysaccharides. Fatty acids (lipids) turn into triglyceride. And amino acids turn into polypeptides (proteins).

64
Q

What are ester bonds?

A

Ester bonds are triglyceride bonds where an acid is bonded with a hydroxyl group.

65
Q

What are peptide bonds?

A

Peptide bonds are an amine bonded with a carboxyl (acid)

66
Q

What does medicine do in terms of active sites?

A

Blocks active sites, stopping the reaction that was bad for the body, or it changes the shape of the enzyme, meaning the enzyme has a different function.

67
Q

What is nucleic acid?

A

Nucleic acid molecules contain genetic information for an organism and make up DNA. DNA instructions make up code for everything, including the amino acid sequence for one specific polypeptide.

68
Q

How do you identify carbohydrates, proteins, and lipids just using their chemical formula?

A

Carbohydrates and lipids both have carbons, hydrogens, and oxygens. Proteins have carbons, hydrogens, oxygens, and nitrogens.

69
Q

What is alpha 1-4 bonding and what is beta 1-4 bonding.

A

Alpha 1 - 4 bonding is when both molecules that are bonded are alpha, beta 1 - 4 bonding is when both molecules that are bonded are beta. Alpha bonding is when the hydroxyl groups that are being bonded together are on the same level (both on the bottom or both on the front). Beta bonding is when the hydroxyl groups being bonded together are on different levels (one on top one on the bottom).

70
Q

What is a maltose?

A

two alpha glucoses bonded together (it is a disaccharide)

71
Q

What is lactose?

A

beta glucose and beta galactose bonded together (it is a disaccharide)

72
Q

What is amylose?

A

A long chain of alpha glucoses (it is a polysaccharide)

73
Q

What is cellulose?

A

It is a chain of beta glucoses (it is polysaccharide). (beta 1- 4 bonding)

74
Q

What is the difference between the structures of amylose and amylopectin?

A

Amylose is bonded in a long chain of 1 - 4 bonds. Amylopectin is bonded in multiple 1 - 4 chains added together with 1 - 6 bonds.

75
Q

What do the terms pentose and hexose mean?

A

Pentose molecules have 5 carbons, and hexose molecules have 6 carbons.

76
Q

What are the words used for multiple saccharides joined together.

A

Disaccharides are 2 saccharides bonded together, polysaccharides are 3 or more.

77
Q

What are the functions of monosaccharides?

A

respiration (cellular) and energy storage (as polysaccharides which are made many monosaccharides)

78
Q

What is an isomer?

A

Isomers are molecules that have the same chemical formula but different structures.

79
Q

Why is glucose versatile?

A

because of its ability to form so many bonds (OH group on nearly every carbon)

80
Q

Why are polysaccharides good sources of energy?

A

because they are easily broken up