Serotonin and prefrontal lobes Flashcards
1
Q
Decreased activity of serotonin neurons is associated with what?
A
Increased risk taking and aggression
2
Q
Prefrontal cortex activated by
A
Serotonin pathway
3
Q
Serotonin releasing drug caused increased
A
Orbitofrontal activation in normal, but not clts with impulsive aggression
4
Q
fMRI study showed lower levels of 5-HT transporters in
A
medial prefrontal areas of clts with impulsive aggression - suggests this area has decreased 5-HT input
5
Q
Pt w/ hx of impulsive aggression - treatment
A
a. fMRI pre-post Fluoxetine treatment
b. increased activity of prefrontal cortex and decrease in aggression
