Antisocial bx + Frontal Lobe

Question 1

What happened to patients with antisocial pd?

Answer 1

Had 11% reduction in gray matter, where they had smaller prefrontal, which gave them less impulse control.

Also unsuccessful psychopaths had 22% reduction in prefrontal gray matter

Question 2

Tell me about PSYCHOPATHY & PFC Thickness?

Answer 2

Lit report shows reduction in prefrontal gray matter volume, gray matter loss in the Right Superior Temporal Gyrus, amygdala, volume loss, decrease in porterior hippocampal vol, exaggerated structural hippocampal asymmetry, and increase in callosal white matter volume in psychopathic individuals.

Question 3

What’s the connection between SEROTONIN and Prefrontal Lobes?

Answer 3

There is decreased activity of SEROTONIN neurons associated with increased risk taking and aggression (as said earlier)

also PFC is activated by large SEROTONIN pathways!

Question 4

What is instrumental aggression?

Answer 4

aggression towards a goal

Question 5

What is impulsive?

Answer 5

emotional flare up causing aggression

Question 6

What happens to SEROTONIN during impulse?

Answer 6

Doesnt activate PFC in this case and it lowers 5-HT transporters.