Serotonin and Dopamine Flashcards by P K

Q

5-HTP (mechanism of action)

A

5-HT (serotonin) precursor

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

5-HTP (indication)

A

Depression

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Buspirone (mechanism of action)

A

HT1A partial agonist

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Buspirone (indication)

A

anxiety/depression

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Sumatriptan (mechanism of action)

A

HT1D agonist

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Sumatriptan (indication)

A

migraine

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Sumatriptan (side effect)

A

coronary vasoconstriction

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Buspirone (side effect)

A

early increase in anxiety

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Risperidone (mechanism of action)

A

HT2A/2C antagonist

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Risperidone (indication)

A

depression/psychosis

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Risperidone (side effect)

A

weight gain; akathesia***

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Odansetron (mechanism of action)

A

HT3

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Odansetron (indication)

A

chemo-induced emesis

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Fluoxetine (mechanism of action)

A

SSRI

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Fluoxetine (indication)

A

depression; OCD; anxiety; panic disorder; PTSD; social phobia

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Fluoxetine (side effect)

A

Sexual dysfunction; insomnia

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Sertraline (mechanism of action)

A

SSRI

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Sertraline (indication)

A

anxiety; social phobia; OCD; PTSD; depression; panic disorder

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Sertraline (side effect)

A

Sexual dysfunction; insomnia

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

L-DOPA (mechanism of action)

A

dopamine precursor

Q

L-DOPA (indication)

A

Parkinson’s disease

Q

L-DOPA (side effect)

A

arrhythmia; dyskinesia

Q

bromocriptine (mechanism of action)

A

D2 agonist

Q

bromocriptine (indication)

A

Parkinson’s disease

carbidopa (mechanism of action)

aromatic acid decarboxylase inhibitor

carbidopa (indication)

Parkinson's disease

carbidopa (side effects)

same as L-DOPA: arrhythmias and/or dyskinesia

selegiline (mechanism of action)

MAO-B inhibitor

selegiline (indication)

Parkinson's disease

talcapone (mechanism of action)

COMT inhibitor

talcapone (indication)

Parkinson's disease

Role of COMT

degrades dopamine, other catecholamines (epi, NE)

methylphenidate (brand name)

Ritalin

methylphenidate (mechanism of action)

dopamine uptake inhibitor

methylphenidate (indication)

ADHD

methylphenidate (side effect)

tachycardia

metaclopramide (mechanism of action)

D2 antagonist

metaclopramide (indication)

nausea

metaclopramide (side effect)

akathasia

haloperidol (mechanism of action)

D2 antagonist

haloperidol (indication)

psychosis

haloperidol (side effect)

extra-pyramidal motor disturbances

dopamine (mechanism of action)

dopamine and adrenergic receptor agonist

dopamine (indication)

shock; cardiac decompensation

dopamine (side effect)

hypotension (low dose); tachycardia

trazadone (mechanism of action)

HT2A/2C antagonist + SSRI

trazadone (indication)

anxiety/depression

trazadone (side effect)

suicidality early after initiation