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26 Autacoids > Serotonin > Flashcards

Serotonin Flashcards

1
Q

Serotonin agonists (4 drugs/groups)

A

Bispirone
Triptans
Ergot drugs
Tegaserod

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2
Q

Triptans (1 drug)

A

Sumatriptan

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3
Q

Serotonin agonists used for migraine headache

A

Triptans (e.g. sumatriptan)

Ergot drugs

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4
Q

Bispirone - indications, which serotonin receptor is activated?

A

Anxiety, depression

5-HT1A-receptors

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5
Q

Activation of which serotonin receptors is useful in migraine treatment?

A

5-HT1D/1B

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6
Q

Serotonin antagonists (7 drugs)

A

Clozapine, cyproheptadine, ondasetron, ganisetron, alosetron, palonosetron, dolasetron

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7
Q

Clozapine - indications

A

Schizophrenia

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8
Q

Which serotonin antagonist has antihistamine activity?

A

Cyproheptadine

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9
Q

Cyproheptadine - indications

A

Allergic reactions

Carcinoid tumor

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10
Q

Which serotonin antagonists are 5-HT2 antagonists? (2 drugs)

A

Clozapine

Cyproheptadine

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11
Q

Which serotonin antagonists are selective 5-HT3 receptor antagonists? (5 drugs)

A 
Ondasetron
Ganisetron
Alosetron
Palosetron
Dolasetron
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12
Q

The 5-HT3 antagonists have which effect in CNS?

A

Blocks serotonin in chemoreceptor trigger zone

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13
Q

Alosetron - indications

A

Women with IBS with diarrhea

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14
Q

Serotonin antagonists used as antiemetics (3 drugs)

A

Ondasetron
Ganisetron
Palosetron

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15
Q

Serotonin reuptake inhibitors are used in?

A

Depression + CNS disorders

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26 Autacoids (3 decks)

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