serotonin 3 receptor antagonists (5HT3RAs) Flashcards
1
Q
3 examples 5HT3RAs
A
ondasetron, granisetron, palonosetron
2
Q
MoA 5HT3RAs
A
5HT inhibited from activating GI afferent fibres/ NTS/ CTZ
3
Q
6 indications 5HT3RAs
A
chemo, radio, post op, post anaesthetics, IBS, hyperemesis gravidarum
4
Q
4 side effects 5HT3RAs
A
constipation, diarrhoea, headaches, prolonged QT interval