serotonin 3 receptor antagonists (5HT3RAs) Flashcards

1
Q

3 examples 5HT3RAs

A

ondasetron, granisetron, palonosetron

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2
Q

MoA 5HT3RAs

A

5HT inhibited from activating GI afferent fibres/ NTS/ CTZ

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3
Q

6 indications 5HT3RAs

A

chemo, radio, post op, post anaesthetics, IBS, hyperemesis gravidarum

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4
Q

4 side effects 5HT3RAs

A

constipation, diarrhoea, headaches, prolonged QT interval

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