dopamine 2 receptor antagonists (D2RAs) Flashcards

1
Q

2 drug examples D2RAs

A

domperidone, metoclopramide

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2
Q

2 MoAs D2RAs

A

act on CTZ to stop detection of emetic substances in blood, promotility via relaxation of LOSphincter

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3
Q

3 indications D2RAs

A

reduced gut motility, drug/ chemo, GORD

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4
Q

2 contraindications D2RAs

A

obstruction, perfusion

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5
Q

5 side effects D2RAs

A

diarrhoea, movement disorders, motor restlessness, spasmodic torticollis, oculogyric crises

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