Serious and Common Adverse Effects

Question 1

What are some serious and common adverse effects of isosorbide dinitrate?

Answer 1

• refractory hypertension, angina from reflex tachycardia, palpitations, syncope
• flushing, headache

Question 2

What are some serious and common adverse effects of isosorbide 5-mononitrate?

Answer 2

• refractory hypertension, angina from reflex tachycardia, palpitations, syncope
• flushing, headache

Question 3

What are some serious and common adverse effects of nitroglycerin

Answer 3

• refractory hypertension, angina from reflex tachycardia, palpitations, syncope
• flushing, headache

Question 4

What are some serious and common adverse effects of sodium nitroprusside?

Answer 4

• cyanide toxicity, cardiac arrhythmia, excessive bleeding, excessive hypotension, metabolic acidosis, bowel obstruction, methmoglobinemia, increased intracranial pressure
• flushing, headache

Question 5

What are some serious and common adverse effects of inhaled nitric oxide gas?

Answer 5

-hypotension, withdrawal syndrome

Question 6

What are some serious and common adverse effects of phosphodiesterase type V inhibitors?

Answer 6

• MI, nonarteritic ischemic optic neuropathy, priapism

- headache, flushing, rash, diarrhea, dyspepsia

Question 7

What are some serious and common adverse effects of dihydropyridines?

Answer 7

• increased angina, rare MI

- palpitations, peripheral edema, flushing, constipation, heartburn, dizziness

Question 8

What are some serious and common adverse effects of benzothiazepine/diltiazem?

Answer 8

• rare cardiac arrhythmia, AV block, bradyarrhythmia, exacerbation of heart failure
• peripheral edema, syncope, gingival hyperplasia, dizziness

Question 9

What are some serious and common adverse effects of phenylalkylamine/verapamil?

Answer 9

• rare cardiac arrhythmia, AV block, bradyarrhythmia, exacerbation of heart failure
• peripheral edema, syncope, gingival hyperplasia, dizziness

Question 10

What are some serious and common adverse effects of potassium channel openers?

Answer 10

• angina, pericardial effusion, reflex tachycardia, Stevens-Johnson syndrome, leukopenia, thrombocytopenia
• headache, flushing, hypotension, hirsutism, hypertrichosis, fluid retention
• headache, flushing

Question 11

What are some serious and common adverse effects of endothelin receptor antagonists?

Answer 11

• hepatotoxicity, anemia, hypotension, fluid retension

- headache, flushing

Question 12

What are some serious and common adverse effects of hydralazine?

Answer 12

• agranulocytosis, leukopenia, hepatotoxicity, systemic lupus erythematous
• headache, palpitations, tachycardia, anorexia, diarrhea