Septic Arthritis Flashcards

1
Q

What is septic arthritis?

A

Acute joint inflammation resulting from intra-articular infection (cartilage + synovial fluid)
Can destroy a joint in <24h
Usually affects knee

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2
Q

Describe the aetiology of septic arthritis

A

May be idiopathic
Usually systemic infection allowing for haematogenous spread but can also be 2nd to direct inoculation of organisms into joint

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3
Q

9 RFs for septic arthritis

A
Recent orthopaedic procedures  
Osteomyelitis 
DM
RA
Prosthetic joints
Immunosuppression 
Alcoholism 
IVDU
Hx of cutaneous ulcers
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4
Q

Describe the epidemiology of septic arthritis

A

Most common in CHILDREN + ELDERLY

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5
Q

List 3 symptoms of septic arthritis

A

Sudden onset
Excruciating joint pain
Lloss of joint function

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6
Q

List 4 signs of septic arthritis

A

Painful, hot, swollen, immobile joint
Erythema
Severe pain prevents passive movement
Pyrexia

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7
Q

What investigations are performed in septic arthritis?

A

Joint aspiration
Blood cultures
Bloods: CBC, CRP, ESR
X-ray

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8
Q

Describe the onset and distribution of septic arthritis

A

Sudden onset, usually monoarthropathy (1 large joint)
May cause polyarthropathy in immunosuppressed
TB arthritis develops more slowly + is more chronic

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9
Q

What are the common causative bacteria of septic arthritis in all age groups?

A

Staphylococcus aureus

TB (suspected in immunocompromised)

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10
Q

What are the common non-bacterial causes of septic arthritis?

A
Rubella  
Mumps  
Hepatitis B 
Parvovirus B19 
Fungi: Candida
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11
Q

What classical triad is seen in patients with septic arthritis?

A

Fever
Joint pain
Restricted range of motion

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12
Q

4 common causative bacteria of septic arthritis in <4s

A

Strep. pneumoniae
Strep. pyogenes
Neisseria meningitidis
Gram-negative rods

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13
Q

Common causative bacteria of septic arthritis in 16-40s

A

Neisseria gonorrhoeae

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14
Q

Describe synovial fluid analysis findings in septic arthritis

A
Grossly purulent- low viscosity, turbid, yellow 
HIGH WCC: Neutrophil dominance
Lower glucose than blood
MC+S for sensitivity
Gram stain
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15
Q

What is an absolute contraindication to joint aspiration in suspected septic arthritis?

A

Infection of skin/ cellulitis surrounding affected joint

Risks introducing pathogen into joint

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16
Q

What additional investigations may be employed if gonococcal arthritis is suspected?

A

PCR from mucosal sites

17
Q

Tx for septic arthritis

A

Serial therapeutic arthrocentesis

Empirical then targeted abx

18
Q

Empiric abx for gram +ve cocci

A

Vancomycin + cefotaxime

19
Q

Empiric abx for gram -ve cocci

A

Ceftriaxone or gentamicin

20
Q

Empiric abx for gram -ve bacilli

A

Ceftriaxone or meropenem

21
Q

Empiric abx for gram stain -ve

A

RF for STD: Ceftriaxone

Np RF for STD: Vancomycin + ceftriaxone