Sepsis, Bacteria and Antibiotics

Question 1

4C Antibiotics

Answer 1

Clindamycin
Cephalosporins
Co-amoxiclav
Ciprofloxacin

Question 2

Antiobiotic management in ESBL producing coliforms

Answer 2

IV meropenem

Question 3

Gram Positive Aerobic Cocci

Answer 3

Staphylococcus

Streptococcus

Question 4

Gram Positive Aerobic Bacilli: Small

Answer 4

Corynebacterium sp

Question 5

Gram Positive Anaerobic Bacilli

Answer 5

Clostridium sp

Question 6

Gram Positive Aerobic Bacilli: Large

Answer 6

Bacillus sp

Question 7

Staphylococci

- Test to differentiate

Answer 7

Coagulase

Question 8

Coagulase negative staphylococci

Answer 8

Staph epidermidis

Question 9

Coagulase positive staphylococci

Answer 9

Staph aureus

Question 10

Streptococci

- Test to differentiate

Answer 10

Haemolysis

Question 11

A Haemolytic Streptococci

Answer 11

Strep pneumoniae
Strep viridans
= partial haemolysis

Question 12

B Haemolytic Streptococci

Answer 12

Group A Strep = strep pyogenes

Group B Strep

Question 13

Non-haemolytic Streptococci

Answer 13

Enterococcus

Question 14

Types of corynebacterium (2)

Answer 14

Corynebacterium diphteriae

Diptheroids

Question 15

Types of clostridium (3)

Answer 15

Cl. tetani
Cl. perfringens
Cl. difficile

Question 16

Gram Negative Strict Aerobes

Answer 16

Legionella sp

Pseudomonas aeruginosa

Question 17

Gram Negative Aerobic Diplococci

Answer 17

Neisseria gonorrhoeae

Neisseria meningitidis

Question 18

Gram Negative Aerobic Bacilli: Small

Answer 18

Bordatella pertussis

Haemophilus influenzae

Question 19

Gram Negative Aerobic Bacilli: Large

Answer 19

Gut commensals
= E.coli, klebsiella, proteus sp
Gut pathogens
= salmonella, shigella, E.coli 0157

Question 20

Gram negative small curved bacilli

Answer 20

Campylobacter sp

Question 21

Gram negative spiral curved bacilli

Answer 21

Helicobacter sp

Question 22

Immunocompromised: association with anti-TNF

Answer 22

M. tuberculosis

Aspergillus (other fungal infections)

Question 23

Antibiotic groups which act on the cell wall

Answer 23

Penicillins
Cephalosporins
Carbopenems
Glycopeptides

Question 24

Examples of penicillins

Answer 24

Penicillin
Amoxicillin
Flucloxacillin

Question 25

Strep organisms - antibiotic used

Answer 25

Penicillin

Question 26

Staph organisms - antibiotic used

Answer 26

Flucloxacillin

Question 27

Enterococcus - antibiotic used

Answer 27

Amoxicillin

Question 28

Examples of cephalosporins

Answer 28

Ceftriaxone | Teftriaxone

Question 29

Cephalosporins are active against - Gram Negative? - Gram Positive?

Answer 29

Active against both | - Have a B-lactam ring

Question 30

Example of glycopeptides

Answer 30

Vancomycin

Question 31

Use of glycopeptides

Answer 31

Used against C. difficile | Active against gram positive anaerobes

Question 32

Antibiotic groups which act on protein synthesis

Answer 32

Macrolides Aminoglycosides Tetracyclines

Question 33

Examples of macrolides

Answer 33

Erythromycin | Clindamycin

Question 34

Examples of aminoglycosides

Answer 34

Iztreonam | Gentamicin

Question 35

Dosing of gentamicin | - Exception

Answer 35

7mg/kg | Increase in obese patients

Question 36

How do you give aminoglycosides?

Answer 36

Can only be given IV

Question 37

Aminoglycosides are active against - Gram Negatives? - Gram Positives?

Answer 37

Gram negatives

Question 38

Examples of tetracyclines

Answer 38

Doxycycline

Question 39

Uses of tetracyclines

Answer 39

Acne and rosacea

Question 40

Tetracyclines are active against - Gram Negatives? - Gram Positives?

Answer 40

Broad spectrum - active against both

Question 41

Antibiotic groups which act on nucleic acid synthesis

Answer 41

Sulphonyamides (Metronidazole) Fluoroquinolones (Rifampicin)

Question 42

Examples of sulphonamide

Answer 42

Trimethoprim

Question 43

Action of sulphonamide | - When not to use

Answer 43

Inhibits folic acid synthesis | - Don't use in the 1st trimester of pregnancy

Question 44

Activity of sulphonamide

Answer 44

Only really acts against E.coli

Question 45

When not to use nitrofurantoin?

Answer 45

In the 3rd trimester of pregnancy

Question 46

When to use metronidazole? | - What organisms active against?

Answer 46

Used in peritonitis | Use against parasites/protozoa/anaerobes

Question 47

Action of metronidazole

Answer 47

Inhibits nucleic acid synthesis

Question 48

Examples of fluoroquinolones

Answer 48

Ciprofloxacin | Levofloxacin

Question 49

Action of fluoroquinolones

Answer 49

Inhibits nucleic acid

Question 50

Action of Rifampicin | - What is it active against?

Answer 50

Inhibits nucleic acid | Active against gram +VE cocci