Alcohol Formative

Question 1

Hepatic Stellate Cells

Answer 1

Intersitial Cells of Ito

Question 2

Interstitial Cells of Ito

Answer 2

They store lipid droplets which are then distributed throughout the liver
= mediate cirrhosis and fibrosis

Question 3

Border of the hepatocytes

Answer 3

Space of Disse

Question 4

Space of Disse

Answer 4

Between the hepatocyte and the sinusoid (small capillary)

Question 5

Usual site for aspiration pneumonia

Answer 5

Apical and posterior segments of the right LOWER LOBE

Question 6

Signs associated with acute pancreatitis

Answer 6

Cullen’s sign

Grey-Turner’s sign

Question 7

Consequence of portal hypertenstion

Answer 7

Massive splenomegaly

Question 8

Cardiac condition associated with chronic alcholism

Answer 8

Dilated cardiomyopathy

Question 9

Metabolism of alcohol

Answer 9

Initial - alcohol dehydrogenase

Question 10

Production of bilirubin

Answer 10

Produced from biliverdin with the enzyme bilverdin reductase

Question 11

Effect of alcohol on HDL levels

Answer 11

Increase

Question 12

Courvoisier’s Sign/Law

Answer 12

In the presence of a palpably enlarged gallbladder which is non-tender and accompanied by mild painless jaundice the cause is unlikely to be gall stones

Question 13

ALP found in…

Answer 13

Placenta
Kidneys
Cells lining the intestine
! Bone and Liver (bile ducts)

Question 14

Acute pancreatitis associated with

Answer 14

Steroid use

Question 15

Antabuse mechanism

Answer 15

Works by inhibiting aldehyde dehydrogenase - the aldehyde remains in the, causing flushing and sickness

Question 16

Jaundice in liver disease or blockage of bile ducts

Answer 16

Conjugated (direct) bilirubin levels

Question 17

Drug causing faster rate of alcohol absorption

Answer 17

Domperidone

Question 18

1g of alcohol calorie content

Answer 18

7

Question 19

Severe hepatitis

Answer 19

Associated with hepatorenal syndrome

Question 20

Diuresis

Answer 20

NOT holding on the water/being dry

- Result of decreased ADH levels