Alcohol Formative Flashcards
Hepatic Stellate Cells
Intersitial Cells of Ito
Interstitial Cells of Ito
They store lipid droplets which are then distributed throughout the liver
= mediate cirrhosis and fibrosis
Border of the hepatocytes
Space of Disse
Space of Disse
Between the hepatocyte and the sinusoid (small capillary)
Usual site for aspiration pneumonia
Apical and posterior segments of the right LOWER LOBE
Signs associated with acute pancreatitis
Cullen’s sign
Grey-Turner’s sign
Consequence of portal hypertenstion
Massive splenomegaly
Cardiac condition associated with chronic alcholism
Dilated cardiomyopathy
Metabolism of alcohol
Initial - alcohol dehydrogenase
Production of bilirubin
Produced from biliverdin with the enzyme bilverdin reductase
Effect of alcohol on HDL levels
Increase
Courvoisier’s Sign/Law
In the presence of a palpably enlarged gallbladder which is non-tender and accompanied by mild painless jaundice the cause is unlikely to be gall stones
ALP found in…
Placenta
Kidneys
Cells lining the intestine
! Bone and Liver (bile ducts)
Acute pancreatitis associated with
Steroid use
Antabuse mechanism
Works by inhibiting aldehyde dehydrogenase - the aldehyde remains in the, causing flushing and sickness
