Antibiotic Man - Treatment of Infections Flashcards

1
Q

CAP Pneumonia 0-2

  • Antibiotics given
  • If PA
A
Amoxicillin 1g tds IV/PO
PA: 
Doxcycline PO 200mg/day on day 1 
Then 
100mg for rest of days
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2
Q

CAP Pneumonia 3-5

  • Antibiotics given
  • If PA
A

Co-amoxiclav IV 1.2g tds + Doxycycline PO 100mg bd

PA: Levofloxacin IV 500mg bd

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3
Q

ICU/HDU Pneumonia

  • Antibiotics given
  • If PA
A

Co-amoxiclav IV 1.2g tds + Clarithromycin IV 500mg bd

PA: Levofloxacin IV 500mg bd

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4
Q

How long do you give antibiotics for in 0-2 CURB65 pneumonia?

A

5 days

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5
Q

How long do you give antibiotics for in 3-5/ICU/HDU pneumonia?

A

7 days

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6
Q

When to give antibiotics in exacerbation of COPD?

A

If there is increased sputum purulence
IF NOT
Don’t give unless there is x-ray evidence of pneumonia

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7
Q

Antibiotics in acute exacerbation of COPD

A

1st - amoxicillin
2nd - doxycycline
- Course for 5 days

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8
Q

Subacute native valve endocarditis

- Antibiotics

A

Amoxicillin IV
Gentamicin IV
(use 1mg/kg maximum 120mg/dose)

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9
Q

Acute/septic native valve endocarditis

- Antibiotics

A

Flucloxacillin IV

2g every 6 hours

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10
Q

Prosthetic valve/suspected MRSA endocarditis

- Antibiotics

A

IV Vancomycin
PO Rifampicin
IV Gentamicin

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11
Q

Non-severe C. difficile infection

- Antibiotics

A

Metronidazole

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12
Q

Severe C. difficile infection

- Antibiotics

A

Vancomycin

+/- Metronidazole

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13
Q

Peritonitis/Biliary Tract/Intra-abdominal infection

  • Antibiotics
  • PA
A

IV amoxicillin + metronidazole + gentamicin

PA: IV vancomycin + metronidazole + gentamicin

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14
Q

Uncomplicated female UTI

- Antibiotic

A

Nitrofurantoin
OR
Trimethoprim
3 days

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15
Q

Uncatherterised male UTI

A

Nitrofurantoin
OR
Trimethoprim
7 days

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16
Q

Which antibiotic doesn’t reach adequate until it is in the bladder?

A

Nitrofurantoin

17
Q

Complicated UTI/pyelonephritis

  • Community
  • Hospital
A
Community: 
Co-amoxiclav 
Co-trimoxazole
14 days 
Hospital: 
IV Amoxicillin 
IV Gentamicin 
3 days
18
Q

SIRS Criteria (4)

A
  1. Body temperature >38 or <36
  2. Heart rate >90/min
  3. Respiratory rate >20/min
    OR
    PaCO2 lower than 32 mmHg
  4. WBC >12 x 109/L or <4 x 109/L