Sepsis And SIRS

Question 1

List the causes of SIRS other than infection

Answer 1

Ischemia
Trauma
Inflammation
Pancreatitis

Question 2

Describe the effects of sepsis on the cardiovascular system

Answer 2

Vasodilation
Deceased CO, SV, BP
Increased HR

Question 3

Describe the difference between infection, systemic inflammatory response and sepsis

Answer 3

Infection - response to invasion of microorganisms

SIRS - clinical response to non-specific insult, characterized by >2 of the following: temp >38 or 90bpm, RR >20, WBC >12000 or 10% immature neutrophils

Sepsis - SIRS + confirmed infectious process. Shock includes >1 organ failure