Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Conditions - Infection > Sepsis > Flashcards

Sepsis Flashcards

1
Q

What is sepsis?

A

Is a life-threatening condition.

When the body’s infection causes injury to its own tissue and organs.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the definition of Organ Dysfunction in sepsis?

A

An acute change in total qSOFA score by more than 2 points after infection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is qSOFA?

A

A screening tool to assess prognosis of SEPSIS. It looks for:

Hypotension
Altered Mental Status
Tachypnoea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is a bad qSOFA score?

A

A score higher than 2 reflects 10% mortality in a general hospital population.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What factors from the HOST may effect presentation of Sepsis? (4)

A

1) Age
2) Comorbidities (COPD / DM)
3) Immunosupression
4) Previous Surgery

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What things can cause a patient to be immunosuppressed? (3)

A
  • Acquired (HIV)
  • Drug Induced
  • Congenital
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What about the ORGANISM may effect presentation of Sepsis? (3)

A

1) Gram +ve / Gram -ve?
2) Virulence factors (for MRSA)
3) Bioburden

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What environments make a person susceptible to sepsis? (3)

A

1) Hospitalisation
2) Occupation
3) Travel

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

How can sepsis present? (7)

A
  • Fever
  • Altered Mental Status
  • Tachycardia
  • Tachypnoea
  • Hypothermia
  • Hypotension
  • Hyperglycaemia
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What are some symptoms which suggest that a patient has a fever? (6)

A
  • Temperature >38°C
  • Chills
  • Rigors
  • Flushes
  • Cold sweats
  • Night sweats
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are some symptoms which suggest that a patient has hypothermia? (4)

A
  • Temperature < 36°C
  • Elderly
  • Very young children

(hypothermia is more likely to present in immunosupressed patients)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is defined as hyperglycaemia?

A

When blood sugar levels above 8mmol/l

in the absence of diabetes.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What inflammatory markers / variables do we look for in patients suspected of sepsis? (5)

A
  • Normal WCC (with >10% immature forms)
  • Leucocytosis
  • Leucopenia
  • High CRP
  • High procalcitonin
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is a high procalcitonin an indicator for?

A

It’s a sign of Active Infection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the biochem definition of leucocytosis?

A

WCC > 12,000/ml

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is the biochem definition of leucopenia?

A

WCC < 4,000/ml

17
Q

What variables suggest organ dysfunction in sepsis? (7)

A
  • Arterial hypoxaemia
  • Coagulation Abnormalities
  • Thrombocytopenia
  • Hyperbilirubinaemia
  • Creatinine Increase
  • Ileus
  • Oliguria
18
Q

What are some haemodynamic variables in sepsis? (2)

A

1) Arterial hypotension
- systolic <90mmHg or
- MAP <70mmHg)

2) SvO2 >70% (venous oxygen)

19
Q

What are some tissue perfusion signs that are apparent in in sepsis? (2)

A
  • High lactate

- Skin mottling & reduced capillary perfusion

20
Q

What is Sepsis6?

A

The treatment plan for SEPSIS.

Take 3, give 3.

21
Q

What are the “take 3” in sepsis6?

A

Take:

1) Blood cultures (microbiology)
2) Blood lactate (hypoperfusion/severe sepsis)
3) Urine output (renal)

22
Q

What are the “give 3” in sepsis6?

A

Give:

1) Oxygen
2) I.V. Antibiotics
3) I.V. Fluid Challenge

23
Q

When do we consider a HDU referral of a sepsis patient? (7)

A
  • Low BP
  • Response to fluids
  • Lactate > 2 (despite fluid resuscitation)
  • Elevated creatinine
  • oliguria
  • liver dysfunction
  • hypoxaemia
  • bilateral inflitrates
24
Q

When do we consider an ITU referral of a sepsis patient? (4)

A
  • Septic shock
  • Requires intubation and ventilation
  • Multi-organ failure
  • Requires sedation
25
Q

What is the progression path of sepsis?

A 
SIRS
--> 
Sepsis
--> 
Severe Sepsis
-->
Septic Shock
26
Q

What is Septic Shock?

A

Dangerously low BP and cellular abnormalities due to sepsis.

27
Q

Why do patients in septic shock need vasopressors to maintain a MAP of >65mmHg?

A

Persisting hypotension

28
Q

What is the hospital mortality rate of septic shock?

A

40%

for every hour delay in administering Abx this increases by 7.6%

29
Q

How do we treat septic shock?

A
  • Take bloods for culture
  • Immediately start Abx therapy
  • Pray to god.

Conditions - Infection (9 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions