Sepsis Flashcards
1
Q
What are risk factors for sepsis
A
>65 years old chronic medical conditions (DM, lung dz, CA, kidney dz) immunocompromised neonates
2
Q
What are the most common sources of sepsis infection’s
A
Lung
urinary tract
skin
G.I. tract
3
Q
What qualifies a sepsis
A
Presumed infection
2+ SIRS criteria
4
Q
What qualifies as severe sepsis
A
Sepsis
organ dysfunction
5
Q
What qualifies a septic shock
A
Sepsis
refractory hypotension
- or lactate >4
6
Q
What is the SIRS (systemic inflammatory response syndrome) criteria
A
Body temp >38°C or <36C
heart rate >90 BPM
tachypnea >20 breaths per minute
wbc count >12,000
7
Q
There is a ___% increase in mortality with every additional as IRS criteria
A
13%
8
Q
What should be done within 3 hours of presentation with sepsis
What should be done within six hours of presentation
A
3hr
- Serum lactate
- blood culture (prior to abx)
- abx
- IV fluids (2.5L/hr) peds= 40 ml/kg
6hr
- Repeat serum lactate if initial lactate >2
- Repeat volume status and tissue perfusion assessment
- give vasopressors
9
Q
What are signs of an organ damage
A
Platelets <100k INR>1.5 or PTT >60 sec lactate >2 MAP <65 mmHG UPO <0.5 ml/kg/hr for >2 hrs or Cr >2 Bilirubin >2.0
