Separation Techniques (Lecture 9)

Question 1

What is the goal of an analytical separation?

Answer 1

to remove either the analyte or the interferent from the sample’s matrix

Question 2

How do we achieve analytical separation?

Answer 2

we must identify at least one significant difference between the analyte’s and the interferent’s chemical or physical properties

Question 3

What two factors limit a separation’s efficiency?

Answer 3

failing to recover all the analyte

failing to remove all the interferent

Question 4

Which techniques achieve separation by size?

Answer 4

filtration
dialysis
size-exclusion chromatography

Question 5

What technique achieves separation by mass or density?

Answer 5

centrifugation

Question 6

What technique achieves separation by complex formation?

Answer 6

masking

Question 7

Which techniques achieve separation by a change in physical state?

Answer 7

distillation
sublimation
re-crystallisation

Question 8

Which techniques achieve separation by a change in chemical state?

Answer 8

precipitation
electrodeposition
volatilisation

Question 9

Which techniques achieve separation by partitioning between phases?

Answer 9

extraction

chromatography