Sensory Physiology (Karius) Flashcards

1
Q

what kind of channels do touch receptors have and what opens them?

A

sodium channel

opened with deformation of the cell membrane

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2
Q

in sensory neurons the start of the action potential is called what

A

generator potential

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3
Q

what are 2 ways to start an action potential

A

if the stimulus is strong enough or lasts long enough

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4
Q

what is the best studied touch receptor

A

pacinian corpuscle

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5
Q

how does the pacinian corpuscle receptor work

A

when touch something all layers of the membrane are deformed, fluid inside membranes
-leads to opening of mechanosensitive Na+ channels on the membrane and influx of sodium

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6
Q

what happens if the stimulus to a touch receptor is maintained

A

action potential gradually die away as adaption occurs

-due to redistribution of the fluid in the corpuscle

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7
Q

what happens with adaption after removal of the stimulus

and what is it called

A

triggers AP as ending reforms, this is an afterdischarge

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8
Q

what is a receptive field

A

area from which stimulation produces activation of the neuron

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9
Q

what are 2 ways to code for intensity of stimulus

A

number of action potentials

pattern of APs

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10
Q

coding stimulus intensity

a change of about ___% is usually required for conscious recognition of the change

A

10%

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11
Q

perceived intensity vs actual intensity depends on what

-2 types

A

type of sensory receptor

  • muscle senses are 1 to 1
  • cutaneous is more variable
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12
Q

dorsal columns are important for

A

proprioceptive and discriminative (fine touch)

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13
Q

spinothalamic tract is important for

A

thermal, nociceptive, and coarse touch (less specific)

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14
Q

pre-synaptic inhibition, neuron A,B,C

A

when C is activated it releases GABA which causes Cl- to enter neuron A and hyperpolarize the cell. not as much calcium can now come in and less NT is released from Neuron A
-reduces AP potential in cell B

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15
Q

where does pre-synaptic inhibition occur?

-purpose?

A

between neighboring receptors at the first synapse in their pathway
-increases brain’s ability to localize signal

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16
Q

each column in the cortex deals with ____ sensory modality in ___ part of the body

17
Q

sensory information arrives at what of the 6 layers in the cortex for a column via __

A

4 via thalamus

18
Q

neighboring coluns receive info from the ____ part of the body but ___ modality

A

same, different sensroy modality

-ex: copuscle touch and thermoreceptor

19
Q

S1 and S2 damage causes what

A

if S1 damaged S2 doesn’t work

if S2 damaged, does not affect S1

20
Q

somatic sensory area 1 location

A

post-central gyrus

broadman’s area 1,2,3

21
Q

somatic sensory area 2 location

A

wall of lateral fissure

22
Q

S1 function

A

integration of the information for position sense as well as size, shape discrimination

  • not complete
  • feeds processing to S2
23
Q

S2 function

A

required for cognitive touch

  • stereognosis
  • comparisons between 2 different tactile sensations
  • determine whether something becomes a memory
24
Q

parieto-temporal-occipital association cortex required for what
-receives input from where

A

required for high-level interpretation of sensory inputs

-receives input from diff sensory cortical areas, including S1 and S2

25
PTO functions with the input it receives
naming of objects | analysis of spatial coordinates of self/surrounding objects
26
if an area of the body is amputated or denervated how does the body respond
afferent input from remaining parts of body will reinnervate the cortex -if not, neurons die
27
how does body respond if area of cortex is lost | what is the trade off?
those afferents will innervate neighboring columns | -localization or specialization is somewhat lost, know what input has hapened but not neccessarily where
28
law of projections
no matter where along the path we stimulate, the perceived sensation is always referred back to the area of the body in which the receptor is located