sensory-physio Flashcards

1
Q

Glycine is antagonized by …

A

Strychnine

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2
Q

Mechanism of action of GABA

A

Increase influx of cl and cause hyperpolarization inhibition

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3
Q

Norepinephrine effects

A

Stimulatory on alpha 1Inhibitory in beta 2 receptors

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4
Q

Effect of NO

A

Change intracellular metabolic function of the brain cells

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5
Q

Glutamate and aspartate receptors

A

NMDA , AMPA and kinate receptors

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6
Q

Muller’s law

A

Each receptor is specific to a certain stimulus and responds to it at low thersold• It can respond to non specific stimulus at high threshold by the same modality of sensation

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7
Q

Weber-fechner law

A

Frequency of AP from receptor to afferent directly proportional to logarithm of intensity on the receptor • If Frequency from recpetor to afferent was 10/100/1000The stimulus intensity on receptor ll be 1/2/3 in order

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8
Q

Skin over angle of mandible

A

Dermatome C2

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9
Q

Skin over sternal angle

A

T2

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10
Q

Skin around nipples

A

T 4

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11
Q

Skin over xiphoid process

A

T 7

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12
Q

Skin around umbilicus

A

T 10

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13
Q

Skin around symphysis pubis

A

T 12

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14
Q

Skin of axilla

A

T 1

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15
Q

Epicritic sensation

A

Fine touch Fast pain Fine degrees of temperatureStereognosisDeep pressureVibration

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16
Q

Protopathic sensations

A

Slow pain Crude touchCrude pressureWide degrees of temp.Itch and tickle

17
Q

Absence sites if nociceptors

A

BoneBrain Liver parenchyma Lung alveoli Visceral layer of internal organs

18
Q

Fast pain characters

A

A delta fibersOnly in skin No summationNT: glutamate Carried neo lateral spinothalamic tract

19
Q

Slow pain characters

A

Afferent: c fibersNT : substance pTract: Paleo lat. spinothalamicSummated

20
Q

1ry hyperalgesia

A

Mechanism: pain receptorsinflamed skin around an injury > non painful cause pain as touch Decreasing of thersold by chemical

21
Q

2ry hyperalgesia

A

Mechanism: convergence facilitatory theory in spinal cord Pain stimulus with normal thersold become more painful in Normal healthy skin

22
Q

Tic duoleureux

A

2ry hyperalgesiaSevere attack of pain of tg 5 and hypoglossal braches 9During laughing and swallowing like an electrical shock

23
Q

Dynamic proprioceptionReceptors

A

Pacinian corpuscles: phasic receptors to detect initial rate of movementRuffiniGolgiMuscle spindleJoint receptors

24
Q

Afferent of medial leminiscal pathway

A

A beta fibers