Sensory Flashcards
Second order neurons in the “through pathway” are namely bipolar cells what are the types and what are they valuable for?
1 x rods, 9 cones and they are important for colour and spatial vision.
What are the features of ganglion cells?
Last cells in the though pathway about 23 different types, break down information into finite units, they have four types ON, OFF, M and P. Only neuron in the Retina that fires AP due to their requirement of signalling across long distances.
Describe the Receptive field properties of a Ganglion cell
Ganglion cells depolarise light by either increasing or decreasing their AP firing rate. The receptive field of a ganglion cell is the area in the retinat that wehn stimulated with light changes the cell’s membrane potential and it fires. Ganglia cells will change their way of firing depending on where in the receptive field you stimulate. They can activate antagonistic centre.s
How can the response of a ganglion cell change and integrate information over time?
Sudden burst of APS at the onset of the stimulus (transient) and sustained through continous APs during stimulation.
How do Ganglion cells convery parallel information?
20 different ganglion cells with 20 different channels of infromation. The different receptor fields properties are the ways in which the image is decoded. Ganglion cells response through increase or decrease in firing or through transient or sustained responses.
Describe the lateral inhibitions of the through pathway.
Horizontal cells: GABA–» respond to light by hyperpolarising–> receive input and coney output onto photoreceptors.
Amarcirne cells: Axonless cells, input from bipolar cells and output on the ganglion cells they usually are important in motion detection and horizontal cells are important in setting up the receptor field. (35-40 different types. Can use glycine and GABA
Describe the output neurons on the retina.
M (parasol) ganglion cells- magnocellular- large, large receptor field, detect motion, flicker and analysis of gross features. (5%) The P ganglion cells more numerous - visual acuity and colour vision (smaller receptor field)- 95%
Both are colour responsive.
Outline the visual pathway
Retina—> Optic nerve—LGN–> Optic radiations—> Visual cortex
Describe the optic chiasm
Fibres from left and right optic nerve—> form at the base of the pituary. Near you internal carotid arteries (main blood supply to your head)
Describe the arrangement of fibres in the lateral geniculate nucleus
Six layers, no integration of the streams of information. M cells (1-2) layers and P cells (3-6)
Optic radiations description
White matter tract formed by the axons of the LGN neurons, large and thick they make the synapse in the PVC.
The projection from the optic radiations is to V1 of the PVC describe the region and its anatomical arrangement
LGN project to the PVC, area 17, occiptal lobe around the calcarine fissure, each half of the visual field is represented by the contralateral VC. Retinotopic organsiation, neighbouring cells within the retina project ti its neighbouring cells in the LGN and Visual cortex.
How is the PVC arranged in terms of input
6 layers of neurons and complexes.
Layer 4c is the input layer from the cortex all receive input from the thalamus in alter 4C where information enters the cortex.
What are the cortical neurons in the VC responding to?
Orientation selectivity neruons are responding to bars of light at particular orientations
Ocular dominance columns
Input from the LGN is segregated into small regions in the PVC called an ocular dominance coloutn