Senescence And The Eye Flashcards

1
Q

Age is accompanied by and increase or decrease in VF

A

Decrease

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2
Q

What causes the VF loss in old age

A

Loss of cells and decrease in the transparency of the ocular media

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3
Q

As we age are we able to tell speed of objects

A

No

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4
Q

What causes the higher incidence of car accidents among elderly

A

The inability to determine the speed of moving objects

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5
Q

What changes occur in the cornea

A

Decreased wound healing

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6
Q

What changes occur in the onrela endothelium

A

Decrease in ell density

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7
Q

What is Corneal arcus

A
  • Most common aging change
  • cholesterol, and cholesterol ester deposits
  • no clinical significance in elderly, but in people under 40 something else could be wrong
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8
Q

By age 50 the occurrence is arcus is______

By age 80?

A

50%

100%

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9
Q

What changes occur in the sclera

A

Fatty deposits cause sclera to yellow

Prtoeoglycans decrease and sclera thins and losses elasticity

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10
Q

What changes occur in the anterior chamber

A

Narrows
(More significant in women)

No age related increase in IOP in healthy people with pressures below 22 mmHG

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11
Q

What changes happen in the iris

A

Dilator muscle becomes strophic, sphincter muscle becomes sclerotic

Harder to dilate the pupil in elderly

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12
Q

What changes occur in the ciliary body

A

No significant correlation between loss of ciliary muscle contractile ability and age

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13
Q

What changes occur in the crystalline lens

A

Presbyopia, cataracts

Patients should use UV protection

Lens grows throughout life

Majority of the increase in thickness occurs between 8-40 y.o.
Also an increase in surface curvatures, forward movement of the center of the lens, decrease in anterior chamber depth

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14
Q

What changes occur into vitreous

A

Vitreous liquefaction (Vitreal syneresis)

As HA dissolves the macromolecules move out of the collagen network, and cause the fibrils to coalesce into fibers an bands

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15
Q

What is PVD

A

One of the most common abnormalities that occurs at the posterior retinal vitreous interface

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16
Q

What is Weiss’ ring

A

When glial tissue is torn away from the vitreous and a circular condensation can be seen in the vitreous

17
Q

What changes occur in the choroid

A

Calcifications and deposits in the inner collagenous layer are responsible for drusen (increase with age)

As lysosomal activity of RPE decreases with age, atypical material may accumulate in Bruchs membrane

18
Q

What changes occur in the lamina cribrosa

A

Nerve fibers passsing through the openings more susceptible to injury, contributing to an increased susceptibility to glaucomatous damage

19
Q

What changes happen in the retina

A

Fovea reflex dims

Accumulations of drusen are located in Bruchs membrane of the choroid are seen as pinpoint deposits in the retina

35-50% of CNS neurons are lost during a lifetime, the # of retinal neurons will decrease with ganglion cell loss

Number of RPE is reduced from 4,000 to 2000

Peripappilary chorioretinal atrophy are pale, temporal crescent, age related degeneration of RPE and Bruchs membrane

Decrease in neuroretinal rim tissue

vertical optic cup diameter and area of theoptic cup both increase

20
Q

What changes occur in the EOMs

A

Constant partial depression may contribute to the impaired ability to elevate the eyes

21
Q

What changes occur in orbital adnexa

A

More pronounced changes in lid margin position (ectropion and entropion)

Increase in incidence with age related changes in orbicularis muscle tone

22
Q

What changes occur in the lacrimal system

A

Tearing may be caused by eversion of the lower punctuation due to eyelid position or stenosis of the assuages in the lacrimal drainage system

-some studies find that the bask rate of tear secretion diminishes after age 40, contributing to dry eye, incidence increases with age

Incidence of vascular engorgement at the lid margin an plugged Meibomian gland pores

23
Q

What changes occur in ocular circulation

A

Endothelial dysfunction can occur with age and can result in increased vascular tone, a reduction in vessel distensibility and decrease in tissue perfusion