Embryology Flashcards

1
Q

The nerve fibers that emerge from the rental ganglion cells at ____ weeks travel along the ______ wall of the _________ to reach the brain

A

6th week
Inner wall
Optic stalk

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2
Q

The lumen of the optic stalk is obliterated by growth of nerve fibers, by week ______, we have a __________

A

8

Solid optic nerve

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3
Q

What are the 2 sources of vascularization

A

Choroidal layer

Hyaloid artery

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4
Q

The hyaloid artery is a _______ artery

A

Transient

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5
Q

What does the hyaloid artery develop from

A

A branch of the ophthalmic artery

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6
Q

What does the hyaloid artery supply

A

The developing retina and lens vesicle

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7
Q

What is the name given to the branches of the hyaloid artery that extend over the lens

A

Tunica vasculosa lentis

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8
Q

The lips of the optic fissue fuse by day______ and enclose this

A

37

Enclose the hyaloid artery

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9
Q

The hyaloid vascualture is maximally developed by what week gestation

A

10

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10
Q

When the lens matures during fetal life and doesn’t need blood supply the hyaloid artery will degenerate. How does this occur

A

Macrophages will eat it

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11
Q

What is the space formed by where the hyaloid artery was

A

Cloquets canal

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12
Q

The proximal portion of the hyaloid artery becomes what?

A

The central retinal artery

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13
Q

What does the central retinal artery supply

A

The retina

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14
Q

Vascularization of the retina starts as the hyaloid artery is regressing and is predominant during the final trimester

A

Know this

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15
Q

In week 6-7 the mesenchyme capsule of the optic cup forms these 2 layers

A

Inner pigmented layer, choroid

Outer fibrous, sclera

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16
Q

The choroid layer is homologous in origin with what 2 things

A

Pia mater

Arachnoid membranes

17
Q

The sclera is ho Olomouc with his

A

Dura mater

18
Q

What does the choroid develop from

A

Neural crest cell-derived mesenchyme and mesoderm

19
Q

What does the sclera develop from

A

Mesenchyme tissue that is continuous with the cornea

20
Q

The cornea has 3 origins. What are they?

A

Head mesoderm: endothelium

Neural crest cells: stroma

Surface ectoderm: outer corneal epithelium

21
Q

Mesenchyme the overlays the lens splits into 2 layers and encloses this new cavity

A

Anterior chamber

22
Q

The anterior wall off the anterior chamber is continuous with this

A

Sclera

23
Q

The posterior wall of the anterior chamber is continuous with this

A

Choroid

24
Q

The pupillary membrane will regress early in fetal period (6-8 mo) and form this

A

Pupil

25
Q

The pupil allows communication between these 2 things

A

Anterior and posterior chamber

26
Q

What happens when the pupillary membrane fails to brain down

A

There are strands that traverse the pupil

27
Q

The Irish stroma develops from this

A

Mesenchyme of both neural crest and mesodermal origin

28
Q

The posterior iris epithelium and the smooth muscle bundles develop from this

A

Neuroepithelium of the optic cup

29
Q

The optic cup differentiates an folds to make

A

Ciliary body

30
Q

The mesenchyme cells that invade the choroid of the ciliary body form this

A

Smooth muscle bundles of the ciliary muscles

31
Q

In week 6, small folds of surface ectoderm develop above and below cornea

They will grow and meet and fuse in this week

A

8th

32
Q

What is the space between the fused eyelids of the cornea called

A

Conjunctival sac

33
Q

The eye lids separate in this month

A

5-7th

34
Q

The eyelid muscles are derived from this

A

Mesoderm

35
Q

The lacrimal glands form from this

A

Invaginations of the surface ectoderm

36
Q

The lacrimal glands do not mature until ______

A

6 weeks after birth

37
Q

Look at the clinical correlates at the end of the lecture

A

Slide 17-19