Self Assessment Flashcards

0
Q

True or false medications can bind with any type of receptor site

A

False

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1
Q

Biochemical effect, physiologic effects, and mechanism of action of a medication

A

Pharmacodynamics

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2
Q

True or false once a medication has interacted with a receptor site, it’s effect on cells are irreversible

A

False

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3
Q

Vasodilation of renal and mensenteric arteries

A

Dopaminergic

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4
Q

Vasoconstriction of arteries and veins

A

Alpha 1

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5
Q

Increased heart rate, increased myocardial contractility, and increased myocardial conduction

A

Beta 1

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6
Q

Allows acetylcholine to stimulate muscle contractility, and increased myocardial conduction

A

Nicotinic

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7
Q

Bronchus and bronchiole relaxation (Bronchodilation)

A

Beta 2

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8
Q

Initiates or alters cellular activity by binding to a receptor site

A

Agonist

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9
Q

Prevents a medication or chemical from binding to a receptor site

A

Antagonist

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10
Q

Is determined by the amount of medication and it’s affinity

A

Potency

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11
Q

The amount of an agonist that must reach threshold level to initiate cellular activity

A

Minimum concentration

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12
Q

The intensity of the attraction and ability of a medication to bind with a receptor site

A

Affinity

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13
Q

The ability of a medication to produce cellular activity and desired therapeutic effects

A

Efficacy

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14
Q

Narcan (Naloxone) Revex (Nalmefene) and Romazicon (flumazenil) are?

A

Antagonist medications

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15
Q

Which type of medication can affect cell, tissue, organ, and system response without binding to a receptor site

A

Sympathomimetic

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16
Q

The amount of medication required to produce desired effects is called the

A

Therapeutic dose

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17
Q

The amount of medication that is less than the lethal dose is called the

A

Toxic dose

18
Q

True or false kidney elimination studies conducted in the investigational phase establish the half-life of a medication

A

False

19
Q

True or false tolerance occurs when some medications have increased efficacy or potency when taken repeatedly by the patient

A

False

20
Q
Each is classified as a stimulant except?
Caffeine 
Benzodiazepines 
Amphetamines 
Cocaine
A

Benzodiazepine

21
Q

Each is characteristic of depressant except?
A transient increase in physical performance
Sedation
Bradycardia
Hypotension

A

A transient increase in physical performance

22
Q

A 22 yr old male has a physical and behavioral need to use heroin in order to maintain normal function. This is called

A

Dependence

23
Q

A 44 yr old female took 3 prescribed antidepressants and 2 mood-elevating herbal supplements resulting in altered mental status. This is called

A

Interference

24
Q

A 22 pound child weighs ______ kg

A

10

25
Q

The length-based pediatric resuscitation device divided into color-coded sections that lists medication doses, endotracheal tube sizes, and defibrillator settings is called the ___________ tape

A

Broselow

26
Q
Physiologic effects of aging include each except 
Decreased-
Cardiac output
Total body water 
Renal function 
Blood volume
A

Blood volume

27
Q

The effects of some medications in women may differ from those of men because of

A

Proportions of body fat and water

28
Q
Physiologic changes in pregnancy include each except
Decreased BP
Increased cardiac output 
Decreased heart rate
Increased respiratory tidal volume
A

Decreased heart rate

29
Q

True or false the placental barrier prevents medications from being exchanged between the mother and the fetus

A

False

30
Q

Which organization created the use-in-pregnancy rating system

A

U.S. Food and Drug Administration

31
Q

The implication of the X pregnancy category is

A

Contraindicated in pregnancy

32
Q

True or false electrolyte-enhanced drinks or substances can slow absorption of most medications and delay therapeutic effects

A

False

33
Q

True or false pharmacogenetics is the process of producing synthetic medications

A

False

34
Q

True or false few medications require repeat doses to maintain therapeutic concentrations in the blood

A

False

35
Q
Each describe intended benefit effect of medication except 
Matriculated response
Desired response 
Therapeutic response
Predictable response
A

Matriculated response

36
Q

After treating a 59 yr old male with 3 nitro tablets for chest pain, you administer an IV infusion of Tridil (nitro) an infusion provides smaller doses of medication to produce the same desired response as larger, single doses
This is called ___________ action

A

Cumulative

37
Q

An action of a medication other than the one for which it was intended

A

Side effect

38
Q

An unintentional, undesirable, and often unpredictable effect of a medication that suggests the possibility of serious consequences

A

Adverse effect

39
Q

An effect that is completely unexpected and unpredictable

A

Idiosyncratic effect

40
Q
Which side effect of a medication is least likely to occur
Stroke
Urticaria 
Dyspnea 
Palpitations
A

Stroke

41
Q

28 yr old female complaining of difficulty breathing and presents with signs and symptoms of asthma. You administer Albuterol and Ipratropium bromide together by small volume nebulizer. The combined administration of 2 meds to produce an effect greater than that of either med individually is called ______ effect

A

Additive

42
Q

75 yr old male accidentally OD on digoxin. You administer digibind and digifab; the 2 meds bind together to inactivate digoxin. This is called

A

Neutralization

43
Q

19 yr old male suffered a closed head injury and you need to perform RSI to secure airway. You administer Midazolam, a benzodiazepine, and Etomidate, a paralytic. By combining the 2 meds, the result has greater effect than the effect of the meds administered alone
This is called

A

Synergism