Selective Serotonin Re-uptake Inhibitors Flashcards
1
Q
Mechanism of action?
A
Selectively inhibit re-uptake of serotonin
2
Q
What is the chemical name for serotonin?
A
5-hydroxytryptamine or 5-HT
3
Q
What are the contra-indications for SSRI use?
A
Poorly controlled epilepsy
If patient enters a manic phase
4
Q
In which neurons in the CNS is serotonin found in high concentrations?
A
Hypothalamus
Limbic system
Medulla
Spinal Cord
5
Q
Other than the CNS, where else in the body is serotonin produced?
A
80-90% of the bodies serotonin is said to be produced in the gastro-intestinal tract.
6
Q
What are the common side effects of SSRIs?
A
Sexual dysfunction Nausea Headache Weight gain Anxiety/restlessness Insomnia Tremors Sweating Dizziness Drowsiness/Fatigue Diarrhoea/constipation Dry mouth
