Seizures (paeds) Flashcards

1
Q

What are stiffening/juddering attacks?

A

Temporary stiffening of upper limbs

Specific to infants

Often around the time of food

Often grow out of them

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2
Q

What is benign sleep myoclonus?

A

Twitches that only occur in the period of time just after falling asleep - ask if it happens when they are awake

If prescribed drugs for epilepsy - these can make them make the twitches happen more

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3
Q

What is a vasovagal syncope?

A

A state similar to a seizure may result from the blood’s inability to return quickly to the brain upon falling after witnessing a certain trigger which results in simultaneous enhancement of parasympathetic nervous system (vagal) tone and withdrawal of sympathetic nervous system tone

Symptoms:
Light headedness, nausea, the feeling of being extremely hot or cold (accompanied by sweating), ringing in the ears, an uncomfortable feeling in the heart, fuzzy thoughts, confusion, a slight inability to speak or form words (sometimes combined with mild stuttering), weakness and visual disturbances such as lights seeming too bright, fuzzy or tunnel vision, black cloud-like spots in vision, and a feeling of nervousness

Typical triggers include:
Prolonged standing
Emotional stress
Pain
The sight of blood

About 33% of people diagnosed with epilepsy have never had a proper seizure and vaovagals are the most common true diagnosis in these instances

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4
Q

How can a frontal lobe seizure present?

A

Fencing posture -
(Because focal)

Then spreads to generalised tonic clonic

Mostly occur at night

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5
Q

What is the definition of myoclonic? How does this differ from clonic? And spasm?

A

Myoclonic = Involves one muscle group; Lasts <100ms

Clonic = involves lots of muscle groups; lasts longer than 100ms, rhythmical contractions

Spasms = in between clonic and myoclonic in length??

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6
Q

What are the terms you use to describe seizures?

A

Focal vs generalised + describe what happens to consciousness (intact/absent/impaired etc)

(no longer simple, complex or partial)

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7
Q

What are the characteristics of absence seizures?

A

Most common between ____yrs, M vs. F?

Quick onset and quick recovery - lasts <10s mostly

Possible motor movements - twitching or mouth movements

Staring/look vacant

Can have 25-30/day

Can be brought on by hyperventilation e.g. get them to blow on a tissue or windmill

May be mistaken for daydreaming, inattention/ADHD, hearing impairment - but these last longer and you can bring someone out of them I.e. by shaking them/tactile stimulation

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8
Q

Why do we treat epilepsy?

A

To keep life as normal as possible for people, improving QoL, improve learning + family dynamic, to avoid stigma

Risk of sudden death - though actually very rare, mor common in those with refractory epilepsy and those who don’t take meds and have seizures at night

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9
Q

Stuff on drugs in kids (this whole deck needs more and rearranging as just contains some of the info from the lecture so far)

A

E

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10
Q

What are some typical EEG patterns for childhood epilepsies?

A

Absence seizures - 3Hz spike and wave pattern, all leads

Childhood epilepsy with central temporal spikes/Benign Rolandic seizures - central and temporal spiking (mouth tingles/twitches, often grow out of)

Infantile spasms - hyperarrhythmia - chaos on an EEG in all leads (poor prognosis)

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11
Q

What affects choice of antiepileptic?

A

Type of seizures - ethosuximide is only used for absence seizures

Sex - often start girls on non-teratogenic meds (so not valproate) as don’t want to gain good control in childhood then have to switch in adolescence; if have to use valproate then may be offered birth control when they become fertile

Side effects - e.g. valproate and weight gain (not great in already obese children)

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12
Q

What is juvenile myoclonic epilepsy?

A

Presentation: clumsiness e.g. dropping cereal is a characteristic sign, especially in the morning as seizures made worse by sleep deprivation (and photostimulation) and all teenagers are sleep deprived

Associated with: absence seizures c.10% - warn parents

Management: levetiracetam/Kepra (most commonly prescribed), valproate, lamotrigine

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13
Q

What are some features of febrile convulsions?

A

Seizure provoked by fever in otherwise healthy child

Typically occur between 6m-5yrs

Rapid rise in temperature is what leads to seizure

Seizures are mostly tonic clonic lasting <5mins (if longer call 999)

Simple febrile seizure:
<15mins 
Generalised 
Typically no recurrence within 24hrs
Complete recovery within 1hr - anything longer may warrant further investigation 

Complex febrile seizure:
15-30 mins (longer = febrile status epilepticus)
Focal seizure
May have repeat seizures within 24hrs

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14
Q

How do you manage febrile seizures?

A

Children who have a first febrile seizure OR any features of a complex febrile seizure should be admitted to paediatrics

No evidence that giving antipyretics promptly can reduce the chance of further seizures - parents may ask, can reassure the it just happens

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15
Q

What is the prognosis for febrile seizures?

A

Overall risk of convulsions if have had on = 1/3

Risk may be greater if:
Age of onset <18m
Fever <39
Shorter duration of fever before seizure 
FHx of febrile convulsions 

May also progress to epilepsy in some:
Strong FHx of epilepsy
Complex febrile seizure
Neurodevelopmental disorders (if have all three factors - 50% change of progressing to epilepsy)

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16
Q

What are infantile spasms?

A

Common in male infants
Often associated with a serious underlying condition and carry a poor prognosis

Features:
characteristic ‘salaam’ attacks: flexion of the head, trunk and arms followed by extension of the arms
this lasts only 1-2 seconds but may be repeated up to 50 times
progressive mental handicap

Investigation:
the EEG shows hypsarrhythmia in two-thirds of infants
CT demonstrates diffuse or localised brain disease in 70% (e.g. tuberous sclerosis)

Management:
poor prognosis
vigabatrin is now considered first-line therapy