Seizures/ Antipsychotic meds Flashcards

1
Q

What type of seizure shows focal discharge at the onset of the seizure on EEG?

A

Simple partial

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2
Q

What type of seizure shows interictal spikes or slow waves in the temporal/ frontotemporal area on EEG?

A

Complex partial

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3
Q

What type of seizure is characterized by a sudden, marked impairment of consciousness without loss of body tone lasting 5-10 seconds?

A

Absence

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4
Q

What type of seizure shows bilateral symmetric 3 Hertz spike wave activity on EEG?

A

Absence

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5
Q

What is the first line medication management for absence seizures?

A

Ethosuximide

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6
Q

What type of seizure is characterized by a sudden LOC with tonic activity followed by 1-2 minutes of clonic followed by postictal confusion?

A

Generalized tonic clonic (grand mal)

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7
Q

How can you rule out pseudo seizures when diagnosing generalized tonic clonic seizures?

A

Increased prolactin and lactic acid immediately after seizures

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8
Q

What type of seizure shows high amplitude rapid spiking on EEG?

A

Generalized tonic clonic

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9
Q

What is the preferred initial management for status epilepticus?

A

Benzodiazepines (Lorazepam)

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10
Q

What is 2nd and 3rd line treatment for status epileptics?

A

(after Lorazepam)
2nd- Phenytoin or Fosphenytoin
3rd- Phenobarbital

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11
Q

What are the SE’s of phenytoin?

A
P450 inducer and induces lupus-like syndrome
Hyperplasia or gums, Hirsutism
Erythema multiforme
Neuropathies
Yield- give slow otherwise hypotension/ arrhythmias
Teratogenic
Osteopenia
Inhibits folic acid absorption
Nystagmus
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12
Q

What is the DOC for trigeminal neuralgia and 2nd line for bipolar disorder and central DI?

A

Carbamazepine

also used for generalized tonic clonic and focal

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13
Q

In what type of seizures should you NOT use Carbamazepine?

A

Absence

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14
Q

What is the DOC for absence seizures?

A

Ethosuximide

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15
Q

What is first line med for acute generalized (tonic clonic) and status epilepticus?

A

Benzodiazepines, Lorazepam

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16
Q

What are notable SE’s of Lorazepam?

A

Sedation, suicide risk

17
Q

What is first line med for myoclonic seizures?

A

Valproic acid, divalproex sodium

18
Q

What is the most notable SE/ contraindication for Valproic acid?

A

Teratogenic

19
Q

What drug can be used for generalized tonic clonic seizures and partial seizures but has a SE of renal stones?

A

Topiramate

20
Q

What drug can be used for partial seizures, peripheral neuropathy, and fibromyalgia?

A

Gabapentin

21
Q

Gabapentin can WORSEN what type of seizure?

A

Absence