Seizures/ Antipsychotic meds Flashcards
What type of seizure shows focal discharge at the onset of the seizure on EEG?
Simple partial
What type of seizure shows interictal spikes or slow waves in the temporal/ frontotemporal area on EEG?
Complex partial
What type of seizure is characterized by a sudden, marked impairment of consciousness without loss of body tone lasting 5-10 seconds?
Absence
What type of seizure shows bilateral symmetric 3 Hertz spike wave activity on EEG?
Absence
What is the first line medication management for absence seizures?
Ethosuximide
What type of seizure is characterized by a sudden LOC with tonic activity followed by 1-2 minutes of clonic followed by postictal confusion?
Generalized tonic clonic (grand mal)
How can you rule out pseudo seizures when diagnosing generalized tonic clonic seizures?
Increased prolactin and lactic acid immediately after seizures
What type of seizure shows high amplitude rapid spiking on EEG?
Generalized tonic clonic
What is the preferred initial management for status epilepticus?
Benzodiazepines (Lorazepam)
What is 2nd and 3rd line treatment for status epileptics?
(after Lorazepam)
2nd- Phenytoin or Fosphenytoin
3rd- Phenobarbital
What are the SE’s of phenytoin?
P450 inducer and induces lupus-like syndrome Hyperplasia or gums, Hirsutism Erythema multiforme Neuropathies Yield- give slow otherwise hypotension/ arrhythmias Teratogenic Osteopenia Inhibits folic acid absorption Nystagmus
What is the DOC for trigeminal neuralgia and 2nd line for bipolar disorder and central DI?
Carbamazepine
also used for generalized tonic clonic and focal
In what type of seizures should you NOT use Carbamazepine?
Absence
What is the DOC for absence seizures?
Ethosuximide
What is first line med for acute generalized (tonic clonic) and status epilepticus?
Benzodiazepines, Lorazepam