Segars Pharm Orientation Flashcards
what are the common parameters of PK
ADME
absorption, distriuution, metabolism, elimanation
field of study of appropriate use of medications to effectively treat or prevent disease and manage symptoms
pharmacotherapeutics
field of study of genetic impact on drug metabolic or handling proces which can affect individual responses to drugs
pharmacogenetics
field of study utilizing scientific and economic methods to evaluate and compare value between therapies
pharmacoeconomics
to be pharmaceutically equivalent drugs need
same ingredients
same dosage form/route
same strength/concentration
meet same standards for quality/purity
what is a pharmaceutical alternatives
same drug but different salts/complexes
-still equivalent
therapeutic equivalence
must be pharmaceutically equivalent and have same
1) therapeutic (clinical) effect
2) safety profile
bioequivalence
similar rate and extent of absorption
80-125% of reference product (brand name)
9 legal requirements of prescriptions
name/address of prescriber name/address of pt dat prescription was written name and strength of medication directions for use quantitiy to be dispensed number of refills allowed prescribers signature prescribers DEA number
non controlled legend lifespan
12 months or # refills
-no legal limit on # of refills or quantity dispensed during 12 month life span
controlled/scheduled legend lifespan
6 months or # of refills
legal limit on number of refills for C3-5
-and quantity
5 refills
90 days
refills for C2 (number and quantity)
none
30 days
partial filling with controlled/scheduled drugs
possible for C3-5 until full quantitiy of prescription and all refills dispensed or expirtation
not possible for C2 unless pharmacist doesn’t have full quantity or long term hospice care
a tsp is how many ml
5 ml