Segars Pharm Lect 1 Flashcards
what are pharmacotherapeutics
study of the appropriate use of medications to effectively treat or prevent disease and manage symptoms
what is pharmacodynamics?
how the drug affects the body- biochemical and physiological effects
what is pharmacokinetics?
how the body affects the drug- time-related physiological process of moving the drug through and out of the body
what is pharmaceutical equivalence?
same ingredients, same dosage form/route, same strength/concentration
Think generics
what is a pharmaceutical alternative?
same therapeutic moiety but different salts, esters, or complexes of that moiety
what is bioequivalence?
similar rate and extent of absorption
– different timing
what is a therapeutic equivalence?
must be pharmaceutically equivalent AND expected to have the same: therapeutic (clinical) effect and safety profile
what is an A FDA rating?
therapeutically equivalent and no bioequivalent issues
a B FDA rating means?
NOT therapeutically equivalent and/or significant bioequivalence issues
what is a pro-drug?
a drug resides in an inactive form, must be metabolized to become active
what are the 2 groups of drugs?
OTC & Behind the counter AND Legend (2 categories)- require prescription
what are the 2 categories of legend drugs?
- scheduled/controlled- habit forming drugs
2. Non-scheduled/non-controlled- not habit forming
Scheduled and controlled drugs are given what sort of designation? means?
CI-CV
Lower risk of abuse the higher the number
C-I have no FDA-approved indications
non-controlled legend drugs last how long?
12 months
which drugs are allowed partial filling?
legend non-controlled
what is the life span of a controlled/scheduled legend?
6 months or # of refills (whichever occurs first)
what is the legal limit of refills for C3-5?
5
what is the legal limit of refills for a C2 drug?
none allowed
what is the one exception to C2 refill law?
terminal hospice patients
what is the quantity allowed to be dispensed for C3-5?
90 days
what is the quantity of C2 allowed to be dispensed?
30 days
which class of drugs are not allowed partial refills? exceptions?
C2
unless: pharmacist doesn’t have full quantity (72 hours), or long-term care/hospice
which classes of controlled/scheduled legend are allowed partial filling?
C3-5 until full quantity of prescription and all refills dispensed or expiration (1 year)
what is pharmacology?
study of drugs and their effects on humans (both positive and negative)
what kinds of prescriptions can PA/NP/etc. write?
non-scheduled, legend drug AND signed collaborative practice agreement/contract
1 kg is equivalent to how many pounds?
2.2lbs
